Pyrpyris Nikolaos, Kritikou Maria, Aggelidis Xenofon, Manolaraki Ioanna, Makris Michael, Papadopoulos Nikolaos G, Xepapadaki Paraskevi
Allergy and Clinical Immunology Unit, 2nd Pediatric Clinic, National and Kapodistrian University of Athens, 115 27 Athens, Greece.
Allergy Unit, 2nd Department of Dermatology and Venereology, Attikon University Hospital, National and Kapodistrian University of Athens, 124 62 Athens, Greece.
J Pers Med. 2022 Sep 30;12(10):1614. doi: 10.3390/jpm12101614.
The European Anaphylaxis Registry (NORA) was designed in order to create a comprehensive Anaphylaxis Registry regarding anaphylactic reactions characteristics and management in several European countries, including Greece. This study aims to analyze Greek data obtained in the NORA framework and describe anaphylaxis' characteristics in this pediatric cohort. An online questionnaire was filled out by the Allergy Unit of the 2nd Pediatric Department of NKUA, regarding reported anaphylaxis characteristics. A total of 284 pediatric patients were analyzed. Patients were predominantly male. A previous, mild reaction (59.5%) to the same allergen was documented in 44.4% of patients. The most common system involved was skin and/or mucosa, followed by the respiratory system. Food was the most common eliciting factor (82.4%). First line treatment was most administered solely by a healthcare professional, followed by a lay person (38.7%). Auto injected adrenaline use by lay persons was third in frequency (29.2%). Most patients received post-reaction counseling and appropriate drug prescription. This study provides insight in anaphylactic cases' characteristics and management in a Greek pediatric cohort. A low rate of adrenaline autoinjector administration was noted in lay people; however, drug prescription and counseling following the reaction could help increase correct acute anaphylaxis management in the future.
欧洲过敏反应登记处（NORA）的设立目的是创建一个关于包括希腊在内的几个欧洲国家过敏反应特征及管理的综合过敏反应登记处。本研究旨在分析在NORA框架下获得的希腊数据，并描述该儿科队列中过敏反应的特征。雅典国立及卡波迪斯特里亚大学第二儿科过敏科填写了一份关于所报告过敏反应特征的在线问卷。总共分析了284名儿科患者。患者以男性为主。44.4%的患者有对相同过敏原先前出现轻度反应的记录（59.5%）。最常累及的系统是皮肤和/或黏膜，其次是呼吸系统。食物是最常见的诱发因素（82.4%）。一线治疗大多仅由医疗专业人员进行，其次是外行人（38.7%）。外行人使用自动注射肾上腺素的频率排第三（29.2%）。大多数患者接受了反应后咨询和适当的药物处方。本研究为希腊儿科队列中过敏反应病例的特征及管理提供了见解。外行人使用肾上腺素自动注射器的比例较低；然而，反应后的药物处方和咨询可能有助于未来提高对急性过敏反应的正确管理。
