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腮腺良性肿瘤的最小切缘手术与术中神经监测:回顾性临床研究

Minimal Margin Surgery and Intraoperative Neuromonitoring in Benign Parotid Gland Tumors: Retrospective Clinical Study.

作者信息

Massimilla Eva Aurora, Motta Giovanni, Magaldi Michelangelo, Montella Marco, Messina Gaetana, Testa Domenico, Cantone Elena, Motta Gaetano

机构信息

Department of Mental, Physical Health and Preventive Medicine-ENT Unit, University of Campania "L. Vanvitelli", 80131 Naples, Italy.

Department of Mental, Physical Health and Preventive Medicine-Pathology Unit, University of Campania "L. Vanvitelli", 80138 Naples, Italy.

出版信息

J Pers Med. 2022 Oct 3;12(10):1641. doi: 10.3390/jpm12101641.

DOI:10.3390/jpm12101641
PMID:36294780
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9604631/
Abstract

Extracapsular dissection (ECD) was introduced for the removal of superficial and small benign parotid tumors. According to a recent proposal, ECD is reserved for tumors that are 3 cm or less, mobile, and close to the parotid borders in cases of pleomorphic adenoma. The aim of the study is to evaluate the effectiveness of ECD for treatment of benign parotid tumors also in cases of tumors that were larger than 3 cm and deeper. All ECD for benign parotid neoplasms conducted between 2007 and 2017 were reviewed. The lesions included were limited to primary parotid tumors and categorized by Quer proposal. Facial nerve monitoring was used in all cases. Facial nerve palsy and local recurrences were assessed. The 88 ECD performed met inclusion criteria. The mean lesion size was 4.26 cm. Of the tumors, 68 were less than 3 cm in diameter and 20 were larger, 64 were superficial, and 24 were deep. The most common lesion types were pleomorphic adenoma (88.6%). There was no significant difference in complication rates between the size of tumor ( = 0.9) and location ( = 0.91). Our results suggest that extracapsular dissection could be considered an option for first-time diagnosed benign parotid tumors, even in cases of large dimensions and deep lobe involvement.

摘要

为切除浅表及小型腮腺良性肿瘤引入了囊外剥离术(ECD)。根据最近的一项提议,在多形性腺瘤病例中,ECD适用于直径3厘米及以下、可移动且靠近腮腺边界的肿瘤。本研究的目的是评估ECD在治疗大于3厘米且位置较深的良性腮腺肿瘤时的有效性。回顾了2007年至2017年间进行的所有腮腺良性肿瘤的ECD手术。纳入的病变仅限于原发性腮腺肿瘤,并根据奎尔提议进行分类。所有病例均使用面神经监测。评估面神经麻痹和局部复发情况。所进行的88例ECD手术符合纳入标准。病变的平均大小为4.26厘米。其中,68个肿瘤直径小于3厘米,20个较大;64个位于浅表,24个位置较深。最常见的病变类型是多形性腺瘤(88.6%)。肿瘤大小(P = 0.9)和位置(P = 0.91)之间的并发症发生率无显著差异。我们的结果表明,即使在肿瘤尺寸较大且累及深叶的情况下,囊外剥离术也可被视为首次诊断的腮腺良性肿瘤的一种选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fba5/9604631/15d2579ebbc8/jpm-12-01641-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fba5/9604631/72dc0c00fc62/jpm-12-01641-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fba5/9604631/44c609e597dc/jpm-12-01641-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fba5/9604631/15d2579ebbc8/jpm-12-01641-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fba5/9604631/72dc0c00fc62/jpm-12-01641-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fba5/9604631/44c609e597dc/jpm-12-01641-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fba5/9604631/15d2579ebbc8/jpm-12-01641-g003.jpg

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本文引用的文献

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2
Analysis of Abdominal Dermal-Fat Grafting to Repair Parotidectomy Defects: An 18-Year Cohort Study.腹部真皮脂肪移植修复腮腺切除术缺损的分析:一项长达 18 年的队列研究。
Laryngoscope. 2020 Sep;130(9):2144-2147. doi: 10.1002/lary.28466. Epub 2020 Jan 7.
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Extracapsular Dissection vs Superficial Parotidectomy of Benign Parotid Lesions: Surgical Outcomes and Cost-effectiveness Analysis.
腮腺肿瘤患者围手术期抑郁和焦虑症状的因素及其对术后并发症和生活质量的影响:一项队列研究
Gland Surg. 2023 Mar 31;12(3):374-385. doi: 10.21037/gs-23-43.
腮腺良性病变的囊外解剖与浅叶腮腺切除术:手术结果及成本效益分析
JAMA Otolaryngol Head Neck Surg. 2017 Nov 1;143(11):1092-1097. doi: 10.1001/jamaoto.2017.1618.
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Surgical options in benign parotid tumors: a proposal for classification.腮腺良性肿瘤的手术选择:一种分类建议。
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