Am J Trop Med Hyg. 1978 Sep;27(5):1015-8. doi: 10.4269/ajtmh.1978.27.1015.
Interrelationships among six patient characteristics recorded upon entry into the trial were analyzed for 67 patients with lepromatous and near-lepromatous leprosy admitted into two chemotherapy trials. Sex was found to be significantly associated with age and with the histopathologic classification; disproportionately large numbers of older patients and of patients classified as borderline-lepromatous (BL) were males. Classifications of the disease process by clinical and histopathologic criteria were closely associated, but many patients classified BL on histopathological grounds were classified fully lepromatous by the clinical criteria. Measurements of the number of Mycobacterium leprae in the patients made by three methods were also significantly correlated. No significant correlations were found between either classification of the disease process on the one hand, and any of the measurements of the numbers of organisms on the other.
对纳入两项化疗试验的67例瘤型和近瘤型麻风患者，分析了入组时记录的6项患者特征之间的相互关系。发现性别与年龄以及组织病理学分类显著相关；老年患者和被分类为界线类偏瘤型（BL）的患者中男性比例过高。根据临床和组织病理学标准对疾病进程的分类密切相关，但许多根据组织病理学分类为BL的患者根据临床标准被分类为纯瘤型。用三种方法对患者体内麻风杆菌数量的测量也显著相关。一方面疾病进程的分类与另一方面任何生物体数量的测量之间均未发现显著相关性。
