Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
Cardiovascular Diseases Institute, 700503 Iasi, Romania.
Medicina (Kaunas). 2022 Oct 2;58(10):1385. doi: 10.3390/medicina58101385.
Aortobronchial fistula is a rare cause of repeated hemoptysis and a potentially fatal condition if left untreated. We present the case of a 40-year-old man with repeated hemoptysis, excessive cough, and epistaxis ongoing for several days after SARS-CoV-2 pneumonia diagnosis. The patient had a history of patch aortoplasty for aortic coarctation and aortic valve replacement with a mechanical valve for aortic insufficiency due to bicuspid aortic valve at the age of 24. Computed tomography scan performed at presentation revealed a severely dilated ascending aorta, a thoracic aorta pseudoaneurysm at the site of the former coarctation, an aortobronchial fistula suggested by the thickened left lower lobe apical segmental bronchus in contact with the pseudoaneurysm and signs of alveolar hemorrhage in the respective segment. The patient was treated with thoracic endovascular aneurysm repair (TEVAR) after prior hemi-aortic arch debranching and transposition of the left common carotid artery and subclavian artery through a closed-chest surgical approach. Our case report together with a systematic review of the literature highlight the importance of both considering an aortobronchial fistula in the differential diagnosis of hemoptysis in patients with prior history of thoracic aorta surgical intervention, regardless of associated pathology, and of taking into account endovascular and hybrid techniques as an alternative to open surgical repair, which carries a high risk of morbidity and mortality.
主动脉支气管瘘是反复咯血的罕见原因,如果不治疗,可能导致致命后果。我们报告了一例 40 岁男性患者,在 SARS-CoV-2 肺炎诊断后数天持续出现反复咯血、剧烈咳嗽和鼻出血。该患者在 24 岁时因二叶式主动脉瓣而患有主动脉缩窄和主动脉瓣关闭不全,曾接受过补丁式升主动脉成形术和机械瓣主动脉瓣置换术。就诊时进行的计算机断层扫描显示升主动脉严重扩张,前缩窄部位的胸主动脉假性动脉瘤,与假性动脉瘤接触的左下叶尖段支气管增厚提示存在主动脉支气管瘘,并在相应节段有肺泡出血迹象。在经胸部闭合手术进行半主动脉弓去分支和左颈总动脉和锁骨下动脉转位后,患者接受了胸主动脉腔内修复术(TEVAR)治疗。我们的病例报告以及对文献的系统回顾强调了无论相关病理学如何,在既往有胸主动脉手术干预史的患者中,将主动脉支气管瘘纳入咯血鉴别诊断的重要性,并且考虑到血管内和杂交技术作为开放手术修复的替代方法,因为开放手术修复风险高,并发症和死亡率都很高。