Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Department of Cardiovascular Surgery, Emergency Clinical Hospital Bucharest, 014461 Bucharest, Romania.
Medicina (Kaunas). 2022 Oct 6;58(10):1404. doi: 10.3390/medicina58101404.
Malignant peripheral nerve sheath tumour (MPNST) is an aggressive and uncommon cancer developing in the peripheral nerve sheath. Primary cardiac MPNST is an extremely rare finding, with no specific imaging and clinical characteristics. Only a handful of cases have been reported in the literature; thus, little is still known about them. Cardiac computed tomography (CT) and cardiac magnetic resonance imaging (CMRI) are important means of assessing cardiac morphology and function. The preferred course of treatment for this pathology is by full surgical resection of the tumour, with negative (clear) margins, followed by adjuvant radiotherapy and chemotherapy. We present the case of a 42-year-old woman with no significant cardiovascular symptoms who was incidentally diagnosed during routine transthoracic echocardiography (TTE) with a cardiac mass located in the left ventricle.
恶性外周神经鞘瘤（MPNST）是一种发生在周围神经鞘的侵袭性和罕见的癌症。原发性心脏 MPNST 是一种极其罕见的发现，没有特定的影像学和临床特征。仅有少数病例在文献中报道；因此，对其了解甚少。心脏计算机断层扫描（CT）和心脏磁共振成像（CMRI）是评估心脏形态和功能的重要手段。这种病理的首选治疗方法是通过完全手术切除肿瘤，并达到阴性（无残留）切缘，然后进行辅助放疗和化疗。我们报告了一例 42 岁女性患者，她没有明显的心血管症状，在常规经胸超声心动图（TTE）检查中偶然发现左心室有心脏肿块。
