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用于可穿戴设备的柔性血氧传感阵列的设计与应用

Design and Application of a Flexible Blood Oxygen Sensing Array for Wearable Devices.

作者信息

Kuo Wen-Cheng, Wu Tzu-Chien, Wang Jun-Sheng

机构信息

Department of Mechatronics Engineering, National Kaohsiung University of Science and Technology, No. 2 Jhuoyue Rd., Nanzih, Kaohsiung 811532, Taiwan.

出版信息

Micromachines (Basel). 2022 Oct 14;13(10):1742. doi: 10.3390/mi13101742.

Abstract

The performance of portable or wearable oximeters is affected by improper movement or wear, which causes an error in the blood oxygen concentration calculation. The error comes from external incident stray light or light leakage caused by the improper fit of the sensor to the skin. This study aimed to develop a flexible blood oxygen sensing system with a 3 × 3 array that uses a reflective-type blood oxygen sensing chip to sequentially measure the blood oxygen levels at nine locations through a time division pulse modulation method. Each sensing chip has light transmission and receiving parts. A flip chip package was used to integrate the sensing chip, and a flexible parylene substrate that could fit the curvature of the wrist and locate the array of photo diodes around the radial artery of the wrist was used. By scanning the sensor array in dynamic behavior, the correct light intensity can be extracted to obtain the blood oxygen concentration and prevent errors due to improper fit or sensor movement during exercise.

摘要

便携式或可穿戴式血氧仪的性能会受到不当移动或佩戴的影响,这会导致血氧浓度计算出现误差。该误差源于外部入射杂散光或传感器与皮肤贴合不当导致的光泄漏。本研究旨在开发一种具有3×3阵列的柔性血氧传感系统,该系统使用反射型血氧传感芯片,通过时分脉冲调制方法依次测量九个位置的血氧水平。每个传感芯片都有光发射和接收部分。采用倒装芯片封装来集成传感芯片,并使用一种能贴合手腕曲率并将光电二极管阵列定位在手腕桡动脉周围的柔性聚对二甲苯基板。通过动态扫描传感器阵列,可以提取正确的光强度,从而获得血氧浓度,并防止运动期间因贴合不当或传感器移动而产生误差。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a28f/9612374/5942d3f257ee/micromachines-13-01742-g001.jpg

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