Harvey A L, Hayashi K
Toxicon. 1987;25(6):681-4. doi: 10.1016/0041-0101(87)90116-4.
A cardiotoxin-like basic polypeptide from the venom of Naja naja atra is homologous to cardiotoxins from the same venom, but much less toxic. To determine if it acts like the cardiotoxins its depolarizing ability was measured. It was about 10 times less potent than the cardiotoxins. Five amino acids are conserved in the sequences studied, on the exposed second and third loops of the toxin backbone. They may be part of the toxins' interactive site.
一种来自眼镜蛇毒的类心脏毒素碱性多肽与同一毒液中的心脏毒素同源,但毒性要小得多。为了确定它是否像心脏毒素那样起作用,对其去极化能力进行了测量。其效力比心脏毒素低约10倍。在所研究的序列中,毒素主链暴露的第二个和第三个环上有五个氨基酸是保守的。它们可能是毒素相互作用位点的一部分。