Hu Nannan, Xu You, Mao Hongjing
Affiliated Mental Health Center and Hangzhou Seventh People's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Front Psychiatry. 2022 Oct 10;13:974888. doi: 10.3389/fpsyt.2022.974888. eCollection 2022.
This survey aimed to better comprehend the factors influencing patient response to insomnia treatment.
We conducted an online survey. A total of 1,395 patients completed the questionnaire at baseline. Insomnia, anxiety and depressive symptoms were evaluated using the Pittsburgh Sleep Quality Index (PSQI), 7-item Generalized Anxiety Disorder assessment (GAD-7) and 9-item Patient Health Questionnaire (PHQ-9), respectively. A total of 488 patients completed at least two surveys (baseline and monthly surveys thereafter) and reported that the online CBT was effective at the 1-year follow-up. The 488 patients were divided into three groups: the rapid (treatment effective at 4 weeks), intermediate (4-16 weeks), and delayed-response group (over 16 weeks).
Analysis of the demographic characteristics of the 488 patients did not reveal significant sex differences among the three groups ( = 0.111). However, the groups significantly differed in age ( = 0.001) and education ( = 0.006). Compared to the rapid response group, the delayed-response group had a higher mean age ( < 0.01) and a slightly lower level of education. The duration of the disorder was longer in the delayed-response group. Multivariate logistic regression showed that male sex, junior high school education, and higher PSQI were independent risk factors for the delayed response to treatment.
Many factors affected the efficiency of insomnia treatment. Male sex, junior school education, and a high PSQI score predicted delayed response to insomnia treatment.
本次调查旨在更好地理解影响患者对失眠治疗反应的因素。
我们开展了一项在线调查。共有1395名患者在基线时完成了问卷。分别使用匹兹堡睡眠质量指数（PSQI）、7项广泛性焦虑障碍评估量表（GAD - 7）和9项患者健康问卷（PHQ - 9）对失眠、焦虑和抑郁症状进行评估。共有488名患者完成了至少两次调查（基线调查及之后的每月调查），并在1年随访时报告在线认知行为疗法有效。这488名患者被分为三组：快速反应组（4周内治疗有效）、中期反应组（4 - 16周）和延迟反应组（超过16周）。
对这488名患者的人口统计学特征分析显示，三组之间在性别上无显著差异（ = 0.111）。然而，三组在年龄（ = 0.001）和受教育程度（ = 0.006）上存在显著差异。与快速反应组相比，延迟反应组的平均年龄更高（ < 0.01），受教育程度略低。延迟反应组的疾病持续时间更长。多因素逻辑回归显示，男性、初中文化程度和较高的PSQI是治疗延迟反应的独立危险因素。
许多因素影响失眠治疗的效果。男性、初中文化程度和较高的PSQI评分预示着对失眠治疗的延迟反应。
