• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Evidence-Based, Mechanistic Approach to the Management of Homozygous Familial Hypercholesterolemia.

作者信息

Rosenson Robert S

机构信息

Metabolism and Lipids, Mount Sinai Health System, New York, New York, USA.

Zena and Michael A. Wiener Cardiovascular Institute, Marie-Josee Center for Cardiovascular Health, Cardiovascular Research Institute, Mount Sinai Heart, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

出版信息

JACC Case Rep. 2022 Oct 19;4(20):1331-1334. doi: 10.1016/j.jaccas.2022.08.017.

DOI:10.1016/j.jaccas.2022.08.017
PMID:36299652
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9588448/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d3f/9588448/77a57dfb2fa2/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d3f/9588448/9e8ef2cd4836/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d3f/9588448/77a57dfb2fa2/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d3f/9588448/9e8ef2cd4836/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d3f/9588448/77a57dfb2fa2/gr1.jpg

相似文献

1
Evidence-Based, Mechanistic Approach to the Management of Homozygous Familial Hypercholesterolemia.基于证据的纯合子家族性高胆固醇血症管理机制方法
JACC Case Rep. 2022 Oct 19;4(20):1331-1334. doi: 10.1016/j.jaccas.2022.08.017.
2
The effect of lomitapide on cardiovascular outcome measures in homozygous familial hypercholesterolemia: A modelling analysis.洛美他派对家族性高胆固醇血症患者心血管结局指标的影响：模型分析。
Eur J Prev Cardiol. 2017 Nov;24(17):1843-1850. doi: 10.1177/2047487317730473. Epub 2017 Sep 19.
3
Lomitapide in homozygous familial hypercholesterolemia: cardiology perspective from a single-center experience.洛美他派在家族性高胆固醇血症纯合子患者中的应用：来自单中心经验的心血管病学视角。
J Cardiovasc Med (Hagerstown). 2018 Mar;19(3):83-90. doi: 10.2459/JCM.0000000000000620.
4
Evinacumab-dgnb (Evkeeza-REGN1500), A Novel Lipid-Lowering Therapy for Homozygous Familial Hypercholesterolemia.依洛尤单抗（瑞百安），一种用于治疗纯合子家族性高胆固醇血症的新型降脂疗法。
Cardiol Rev. 2024;32(2):180-185. doi: 10.1097/CRD.0000000000000522. Epub 2023 Apr 18.
5
The Role of Non-statin Lipid-Lowering Medications in Youth with Hypercholesterolemia.非他汀类降脂药物在青少年高胆固醇血症中的作用。
Curr Atheroscler Rep. 2022 May;24(5):379-389. doi: 10.1007/s11883-022-01013-x. Epub 2022 Mar 28.
6
Treating homozygous familial hypercholesterolemia in a real-world setting: Experiences with lomitapide.在现实环境中治疗纯合子家族性高胆固醇血症：洛美他派的应用经验
J Clin Lipidol. 2015 Jul-Aug;9(4):607-17. doi: 10.1016/j.jacl.2015.05.001. Epub 2015 May 14.
7
Safety and Efficacy of Lomitapide in Japanese Patients with Homozygous Familial Hypercholesterolemia (HoFH): Results from the AEGR-733-301 Long-Term Extension Study.洛美他派在日本纯合子家族性高胆固醇血症（HoFH）患者中的安全性和疗效：AEGR-733-301 长期扩展研究结果。
J Atheroscler Thromb. 2019 Apr 1;26(4):368-377. doi: 10.5551/jat.45708. Epub 2018 Sep 26.
8
New Frontiers in the Treatment of Homozygous Familial Hypercholesterolemia.新型治疗纯合子家族性高胆固醇血症的方法。
Heart Fail Clin. 2022 Jan;18(1):177-188. doi: 10.1016/j.hfc.2021.07.008. Epub 2021 Oct 22.
9
Microsomal triglyceride transfer protein inhibitor (lomitapide) efficacy in the treatment of patients with homozygous familial hypercholesterolaemia.微粒体甘油三酯转移蛋白抑制剂（洛美他派）治疗纯合子家族性高胆固醇血症患者的疗效。
Eur J Prev Cardiol. 2020 Jan;27(2):157-165. doi: 10.1177/2047487319870007. Epub 2019 Aug 12.
10
New LDL-cholesterol lowering therapies: pharmacology, clinical trials, and relevance to acute coronary syndromes.新型 LDL 胆固醇降低治疗方法：药理学、临床试验及与急性冠脉综合征的相关性。
Clin Ther. 2013 Aug;35(8):1082-98. doi: 10.1016/j.clinthera.2013.06.019. Epub 2013 Aug 8.

引用本文的文献

1
Clogged Arteries, Safety Net Holes: Treating an Underinsured Patient for Homozygous Familial Hypercholesterolemia With Plasmapheresis.动脉堵塞、安全网漏洞：用血浆置换法治疗一名患有纯合子家族性高胆固醇血症的未充分参保患者
Cureus. 2024 Sep 25;16(9):e70174. doi: 10.7759/cureus.70174. eCollection 2024 Sep.

本文引用的文献

1
Implementation of Novel Lipid Therapies in a Refractory Heterozygous Familial Hypercholesterolemia Patient With Atherosclerotic Disease.新型脂质疗法在一名患有动脉粥样硬化疾病的难治性杂合子家族性高胆固醇血症患者中的应用。
JACC Case Rep. 2022 Oct 19;4(20):1327-1330. doi: 10.1016/j.jaccas.2022.06.021.
2
New Therapies for Lowering Triglyceride-Rich Lipoproteins: JACC Focus Seminar 3/4.降低富含甘油三酯脂蛋白的新疗法：JACC 焦点研讨会 3/4。
J Am Coll Cardiol. 2021 Nov 2;78(18):1817-1830. doi: 10.1016/j.jacc.2021.08.051.
3
Existing and emerging therapies for the treatment of familial hypercholesterolemia.
治疗家族性高胆固醇血症的现有和新兴疗法。
J Lipid Res. 2021;62:100060. doi: 10.1016/j.jlr.2021.100060. Epub 2021 Mar 12.
4
Evinacumab for Homozygous Familial Hypercholesterolemia.依洛尤单抗治疗纯合子家族性高胆固醇血症。
N Engl J Med. 2020 Aug 20;383(8):711-720. doi: 10.1056/NEJMoa2004215.
5
Efficacy and Safety of Alirocumab in Adults With Homozygous Familial Hypercholesterolemia: The ODYSSEY HoFH Trial.依洛尤单抗在杂合子家族性高胆固醇血症成人患者中的疗效和安全性：ODYSSEY HoFH 试验。
J Am Coll Cardiol. 2020 Jul 14;76(2):131-142. doi: 10.1016/j.jacc.2020.05.027.
6
Effect of Bempedoic Acid vs Placebo Added to Maximally Tolerated Statins on Low-Density Lipoprotein Cholesterol in Patients at High Risk for Cardiovascular Disease: The CLEAR Wisdom Randomized Clinical Trial.贝匹地酸对比安慰剂联合最大耐受他汀类药物治疗对心血管疾病高危患者的低密度脂蛋白胆固醇的影响：CLEAR Wisdom 随机临床试验。
JAMA. 2019 Nov 12;322(18):1780-1788. doi: 10.1001/jama.2019.16585.
7
Long-Term Efficacy and Safety of the Microsomal Triglyceride Transfer Protein Inhibitor Lomitapide in Patients With Homozygous Familial Hypercholesterolemia.微粒体甘油三酯转运蛋白抑制剂洛美他派治疗纯合子家族性高胆固醇血症患者的长期疗效和安全性
Circulation. 2017 Jul 18;136(3):332-335. doi: 10.1161/CIRCULATIONAHA.117.028208.
8
Systematic Review of Low-Density Lipoprotein Cholesterol Apheresis for the Treatment of Familial Hypercholesterolemia.低密度脂蛋白胆固醇血浆置换治疗家族性高胆固醇血症的系统评价
J Am Heart Assoc. 2016 Jul 6;5(7):e003294. doi: 10.1161/JAHA.116.003294.
9
Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society.纯合子家族性高胆固醇血症：临床医生提高检测和临床管理水平的新见解与指南。欧洲动脉粥样硬化学会家族性高胆固醇血症共识小组的立场文件。
Eur Heart J. 2014 Aug 21;35(32):2146-57. doi: 10.1093/eurheartj/ehu274. Epub 2014 Jul 22.