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[谷胱甘肽:兔眼组织中的脱氢抗坏血酸氧化还原酶活性]

[Glutathione:dehydroascorbate oxidoreductase activity in rabbit eye tissues].

作者信息

Bogdanova I A, Gerasimov A M, Komarov O S

出版信息

Vopr Med Khim. 1987 May-Jun;33(3):104-7.

PMID:3630002
Abstract

Glutathione: dehydroascorbate oxidoreductase was detected in rabbit eye tissues, activity of which was decreased as compared with that of glutathione reductase. The ratio between glutathione reductase activity and the total activity of the enzymes catalyzing glutathione oxidation (glutathione: dehydroascorbate oxidoreductase and glutathione: H2O2 peroxidase) was above one unit in cornea, ciliary body, sclera vascular tunic and iris of the eye; it was lower than one unit in vitreous body, lens, optic nerve and aqueous humor. Glutathione: dehydroascorbate oxidoreductase is one of the key component in the eye antioxidative system; it regulates the ratio of oxidized and reduced forms of ascorbic acid and glutathione.

摘要

谷胱甘肽

脱氢抗坏血酸氧化还原酶在兔眼组织中被检测到,其活性与谷胱甘肽还原酶相比有所降低。在角膜、睫状体、巩膜血管膜和虹膜中,谷胱甘肽还原酶活性与催化谷胱甘肽氧化的酶(谷胱甘肽:脱氢抗坏血酸氧化还原酶和谷胱甘肽:过氧化氢过氧化物酶)的总活性之比高于一个单位;在玻璃体、晶状体、视神经和房水中则低于一个单位。谷胱甘肽:脱氢抗坏血酸氧化还原酶是眼部抗氧化系统的关键成分之一;它调节抗坏血酸和谷胱甘肽氧化型与还原型的比例。

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