Hempel G, Schubert K, Fritz T, Platzbecker H, Reinhardt F, Wünschmann H J
Z Gesamte Inn Med. 1987 Apr 15;42(8):205-9.
Among 27,756 cases with stationary treatment 1,532 patients were found in whom a systemic fibrinolysis therapy was taken into consideration. Under strict attention to indications and contraindications 173 patients were treated with streptokinase. The rate of treatment failures in peripheral arterial obstructions was 46%, in venous thromboses 29%. The lethality of pulmonary embolisms could be decreased significantly, in acute myocardial infarction however, it could not be reduced. In 10% of the cases we observed severe therapeutic complications. The systemic streptokinase therapy is therefore a certainly effective, but also high-risk method of treatment, which must be performed by an experienced physician.
在27756例接受固定治疗的病例中，发现有1532名患者考虑进行全身纤维蛋白溶解疗法。在严格注意适应证和禁忌证的情况下，173例患者接受了链激酶治疗。外周动脉阻塞的治疗失败率为46%，静脉血栓形成的治疗失败率为29%。肺栓塞的致死率可显著降低，但在急性心肌梗死中，致死率无法降低。在10%的病例中，我们观察到严重的治疗并发症。因此，全身链激酶疗法是一种确实有效的但也是高风险的治疗方法，必须由经验丰富的医生进行操作。
