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知识渊博、有认知/感兴趣:年轻黑人女性对暴露前预防的看法。

Knowledgeable, aware / interested: Young black women's perceptions of pre-exposure prophylaxis.

作者信息

Haider Sadia, Friedman Eleanor E, Ott Emily, Moore Amy, Pandiani Agustina, Desmarais Catherine, Johnson Amy K

机构信息

Department of Obstetrics and Gynecology, Rush University Medical Center, Chicago, IL, United States.

Department of Obstetrics and Gynecology, University of Chicago, Chicago, IL, United States.

出版信息

Front Reprod Health. 2022 Sep 30;4:671009. doi: 10.3389/frph.2022.671009. eCollection 2022.

Abstract

PURPOSE

HIV in the United States disproportionately affects young Black women. Pre-exposure prophylaxis (PrEP) is an effective HIV prevention option that has the potential to reduce HIV incidence among HIV-vulnerable populations. However, data regarding women's awareness, interest in starting, and feelings of acceptability or stigma about PrEP remains limited, particularly among adolescent and young Black women.

MATERIALS AND METHODS

A cross-sectional survey was conducted with 100 sexually active young Black women ages 13-24 years attending women's health clinics in Chicago, IL. Descriptive statistics were used to characterize the sample and determine more about what the PrEP needs and barriers are in this community. Associations were modeled using logistic regression and 95% confidence intervals for both bivariate and multivariable models.

RESULTS

In our survey ( = 100), half of study participants (50%) expressed interest in starting PrEP in the next three months and a majority (80%) of young women were confident they could obtain PrEP. Pregnant young women were significantly more interested in starting PrEP than non-pregnant women [OR 2.3 95% CI (1.0, 5.4)],  = 0.05), however, this association did not remain significant in adjusted models.

CONCLUSIONS

This study provides a more complete understanding of awareness, interest in, and acceptability of PrEP among adolescent and young Black women attending women's health clinics. Findings indicate sustained interest in starting PrEP, reduced stigma, and increased awareness of PrEP among young Black women. These findings suggest that integrating PrEP into women's health clinics is a promising strategy to increase awareness and utilization of PrEP and decrease HIV transmission among youth at highest risk.

摘要

目的

在美国,艾滋病毒对年轻黑人女性的影响尤为严重。暴露前预防(PrEP)是一种有效的艾滋病毒预防方法,有可能降低艾滋病毒易感人群中的艾滋病毒感染率。然而,关于女性对PrEP的知晓情况、开始使用的意愿以及对PrEP的可接受性或耻辱感的数据仍然有限,尤其是在青少年和年轻黑人女性中。

材料与方法

对伊利诺伊州芝加哥市女性健康诊所的100名年龄在13 - 24岁之间有性行为的年轻黑人女性进行了横断面调查。描述性统计用于描述样本特征,并进一步确定该社区对PrEP的需求和障碍。使用逻辑回归对双变量和多变量模型进行关联建模,并计算95%置信区间。

结果

在我们的调查(n = 100)中,一半的研究参与者(50%)表示有兴趣在未来三个月开始使用PrEP,大多数(80%)年轻女性相信她们能够获得PrEP。怀孕的年轻女性比未怀孕的女性对开始使用PrEP更感兴趣[比值比2.3,95%置信区间(1.0,5.4),P = 0.05],然而,在调整模型中这种关联不再显著。

结论

本研究更全面地了解了在女性健康诊所就诊的青少年和年轻黑人女性对PrEP的知晓情况、兴趣以及可接受性。研究结果表明年轻黑人女性对开始使用PrEP持续感兴趣,耻辱感降低,对PrEP的认识有所提高。这些发现表明,将PrEP纳入女性健康诊所是一种有前景的策略,可提高对PrEP的认识和使用率,并减少高危青年中的艾滋病毒传播。

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