Osama Muhammad, Faisal Hafsa, Din Mohammad Ammad Ud, Mahmoud Amir, Hussain Syed Ather, Verghese Basil
Department of Internal Medicine, Rochester General Hospital, Rochester, New York.
Proc (Bayl Univ Med Cent). 2022 Jul 25;35(6):846-848. doi: 10.1080/08998280.2022.2100176. eCollection 2022.
Extramedullary and nonlymphoid organ involvement in chronic lymphocytic leukemia (CLL) is exceedingly rare, with only a few cases of bladder infiltration reported to date. Here, we present a case of a 71-year-old man with advanced-stage CLL who presented with gross hematuria initially thought to be secondary to a urinary tract infection. However, a cystoscopy with biopsy confirmed the diagnosis of extramedullary CLL with bladder involvement. The patient was started on venetoclax with improvement in symptoms and no recurrence of hematuria.
慢性淋巴细胞白血病(CLL)累及髓外非淋巴器官极为罕见,迄今为止仅有少数膀胱浸润病例报道。在此,我们报告一例71岁晚期CLL男性患者,最初因肉眼血尿就诊,初步认为是继发于尿路感染。然而,膀胱镜检查及活检确诊为累及膀胱的髓外CLL。患者开始使用维奈克拉治疗后症状改善,血尿未再复发。