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尿路上皮癌附近的淋巴细胞浸润类型对慢性淋巴细胞白血病具有诊断意义。

The type of lymphocyte infiltration near urothelial carcinoma is diagnostic for chronic lymphocytic leukemia.

作者信息

Baseskiogulu Barbaros, Canaz Funda, Kaya Coskun, Dönmez Turgut

机构信息

Department of Urology and Pathology, Faculty of Medicine, Osmangazi University, Eskisehir, Turkey.

出版信息

Urol Ann. 2013 Jan;5(1):47-9. doi: 10.4103/0974-7796.106968.

DOI:10.4103/0974-7796.106968
PMID:23662012
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3643325/
Abstract

T-lymphocytic infiltration near the tumor site is an expected immune response in bladder cancers. However, reports of patients with bladder cancer exhibiting small lymphocytic infiltration of the bladder tissue are very rare in the literature. Here, the patient was presented to our group with hematuria, but subsequently diagnosed as exhibiting invasive bladder cancer and chronic lymphocytic leukemia with suspicious lymphocytic infiltration in a transurethral resection specimen. This case emphasizes the importance of lymphocytic infiltration's nature near urothelial carcinoma.

摘要

肿瘤部位附近的T淋巴细胞浸润是膀胱癌中预期的免疫反应。然而,文献中关于膀胱癌患者膀胱组织淋巴细胞浸润较少的报道非常罕见。在此,该患者因血尿前来我院就诊,但随后经诊断为浸润性膀胱癌和慢性淋巴细胞白血病,经尿道切除标本中可见可疑的淋巴细胞浸润。该病例强调了尿路上皮癌附近淋巴细胞浸润性质的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31f2/3643325/6fc45bb3fab0/UA-5-47-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31f2/3643325/4cbb954a4b5a/UA-5-47-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31f2/3643325/372cc35a87d1/UA-5-47-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31f2/3643325/6fc45bb3fab0/UA-5-47-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31f2/3643325/4cbb954a4b5a/UA-5-47-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31f2/3643325/372cc35a87d1/UA-5-47-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31f2/3643325/6fc45bb3fab0/UA-5-47-g003.jpg

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Relationship between glutathione S-transferase M1, T1, and P1 polymorphisms and chronic lymphocytic leukemia.谷胱甘肽S-转移酶M1、T1和P1基因多态性与慢性淋巴细胞白血病的关系
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