阿扎胞苷诱发的急性髓系白血病患者的心肌心包炎
Azacitidine-induced myopericarditis in acute myeloid leukemia.
作者信息
Ismayl Mahmoud, Kc Asmini, Thandra Abhishek, Sricharoen Nattapong, Arouni Amy
机构信息
Department of Internal Medicine, Creighton University School of Medicine, Omaha, Nebraska.
Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska.
出版信息
Proc (Bayl Univ Med Cent). 2022 Aug 18;35(6):849-851. doi: 10.1080/08998280.2022.2111642. eCollection 2022.
Hypomethylating agents are commonly used in the treatment of myelodysplastic syndromes and are known to cause bone marrow suppression; however, cardiac complications are rare. We describe a patient who was diagnosed with acute myeloid leukemia and developed myopericarditis after receiving chemotherapy with azacitidine. Our case highlights the importance of a thorough history, including medication review, in patients with suspected myopericarditis. It also raises awareness about the potential cardiac side effects of azacitidine.
去甲基化药物常用于治疗骨髓增生异常综合征，已知会导致骨髓抑制；然而，心脏并发症很少见。我们描述了一名被诊断为急性髓系白血病的患者，在接受阿扎胞苷化疗后发生了心肌心包炎。我们的病例强调了对于疑似心肌心包炎患者进行全面病史询问（包括用药回顾）的重要性。它还提高了人们对阿扎胞苷潜在心脏副作用的认识。
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