磁共振电阻抗断层成像。

Magnetic Resonance Electrical Impedance Tomography.

机构信息

School of Biological Health System Engineering, Arizona State University, Tempe, AZ, USA.

出版信息

Adv Exp Med Biol. 2022;1380:157-183. doi: 10.1007/978-3-031-03873-0_7.

Abstract

Magnetic Resonance Electrical Impedance Tomography (MREIT) is a high-resolution bioimpedance imaging technique that has developed over a period beginning in the early 1990s to measure low-frequency (<1 kHz) tissue electrical properties. Low-frequency electrical properties are particularly important because they provide valuable information on cell structures and ionic composition of tissues, which may be very useful for diagnostic purposes. MREIT uses one component of the magnetic flux density data induced due to an exogenous-current administration, measured using an MRI machine, to reconstruct isotropic or anisotropic electrical property distributions. The MREIT technique typically requires two linearly independent current administrations to reconstruct conductivity uniquely. Since its invention, researchers have explored its potential for measuring electrical conductivity in regions such as the brain and muscle tissue. It has also been investigated in disease models, for example, cerebral ischemia and early tumor detection. In this chapter, we aim to provide a solid foundation of the different MREIT image reconstruction algorithms, including both isotropic and anisotropic conductivity reconstruction approaches. We will also explore the newly developed diffusion tensor magnetic resonance electrical impedance tomography (DT-MREIT) method, a practical method for anisotropic tissue property imaging, at the end of the chapter.

摘要

磁共振电阻抗断层成像(MREIT)是一种高分辨率生物电阻抗成像技术,它始于 20 世纪 90 年代初,用于测量低频(<1 kHz)组织电特性。低频电特性尤为重要,因为它们提供了有关细胞结构和组织离子组成的有价值信息,这对于诊断目的可能非常有用。MREIT 使用磁共振成像(MRI)机器测量的外源电流引起的磁通量密度数据的一个分量,来重建各向同性或各向异性的电特性分布。MREIT 技术通常需要两次线性独立的电流注入来唯一重建电导率。自发明以来,研究人员一直在探索其在测量大脑和肌肉组织等区域的电导率方面的潜力。它还在疾病模型中进行了研究,例如脑缺血和早期肿瘤检测。在本章中,我们旨在为不同的 MREIT 图像重建算法提供坚实的基础,包括各向同性和各向异性电导率重建方法。我们还将在本章的最后探讨新开发的扩散张量磁共振电阻抗断层成像(DT-MREIT)方法,这是一种用于各向异性组织特性成像的实用方法。

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