Djawari D, Hornstein O P
Arch Dermatol Res. 1978 Sep 28;263(1):97-104.
The function of microphages has been studied in two patients with chronic pyoderma vegetans by in vitro determination of phagocytosis as well as chemotaxis. The results showed a striking decrease in the chemotactic activity of the neutrophil granulocytes, a reduced phagocytosis of Candida albicans and Staphylococcus aureus, and a weakness of the intracellular killing of these microorganisms. However, the NADH-dependent oxidase activity appeared to be intact. No defect was found in the specific cellular or humoral immune system in either patient.
通过体外测定吞噬作用和趋化性，对两名慢性增殖性脓皮病患者的巨噬细胞功能进行了研究。结果显示，中性粒细胞的趋化活性显著降低，白色念珠菌和金黄色葡萄球菌的吞噬作用减弱，以及对这些微生物的细胞内杀伤能力不足。然而，NADH依赖性氧化酶活性似乎完好无损。两名患者的特异性细胞或体液免疫系统均未发现缺陷。
