Yokose T, Doi M, Kimura Y, Ogata T
Acta Pathol Jpn. 1987 Jun;37(6):1033-40. doi: 10.1111/j.1440-1827.1987.tb00454.x.
In the present paper, numerous micro-communications between myocardial sinusoids and small branches of coronary arteries are studied which existed in a rudimentary right ventricle of a female neonate with pulmonary atresia and an intact ventricular septum, who was born on the 40th week of gestation. Cardioangiography revealed a large fistulous subepicardial communication. At autopsy, myocardium of the right ventricle appeared spongy with extensive sinusoid slits. In addition to the large communication which was connecting a deeply extending sinusoid of the right ventricle to the main trunk of the anterior descending artery, numerous micro-communications were found between myocardial sinusoids in the rudimentary right ventricle and intramural small branches of the coronary artery. Furthermore, morphometrical analysis demonstrated that the medias of the intramural arteries in both ventricles of the present case were significantly hypertrophic, as compared with those in the control cases without communications (p less than 0.05). These facts indicate the significance of hemodynamic factors on the persistence of embryonic sinusoid-coronary communication.
在本文中，对一名孕40周出生的患有肺动脉闭锁且室间隔完整的女新生儿的未发育完全的右心室中心肌血窦与冠状动脉小分支之间的众多微交通进行了研究。心血管造影显示有一个大的瘘管样心外膜下交通。尸检时，右心室心肌呈海绵状，有广泛的血窦裂隙。除了将右心室一个深入延伸的血窦与前降支主干相连的大交通外，在未发育完全的右心室心肌血窦与冠状动脉壁内小分支之间还发现了众多微交通。此外，形态计量分析表明，与无交通的对照病例相比，本病例两心室壁内动脉的中膜明显肥厚（p小于0.05）。这些事实表明血流动力学因素对胚胎血窦 - 冠状动脉交通持续存在的重要性。
