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接受关节手术的类风湿关节炎患者滑液中的单核细胞。

Mononuclear cells in synovial fluid of rheumatoid arthritis patients undergoing joint surgery.

作者信息

Lautenschlager I, Kankaanpää U, Kontiainen S

出版信息

Acta Pathol Microbiol Immunol Scand C. 1987 Jun;95(3):123-7. doi: 10.1111/j.1699-0463.1987.tb00019.x.

DOI:10.1111/j.1699-0463.1987.tb00019.x
PMID:3630716
Abstract

Analysis of synovial fluid from patients with rheumatoid arthritis (RA) and a long history of RA, who were undergoing synovectomy and joint surgery, revealed that 71 +/- 15% of the mononuclear cells in the synovial fluid were lymphocytes. 3 +/- 2% lymphoid blast cells, and 26 +/- 15% of monocytes/macrophages. The lymphocyte population consisted mainly of T cells, and 72 +/- 15% of lymphocytes were OKT11-positive. OKT8-positive cells (48 +/- 9%) dominated over OKT4-positive (32 +/- 8%) cells with a mean OKT4/OKT8 ratio of 0.69. On the basis of Ia- and Tac-markers, very few of the lymphocytes were activated. Few B cells (12 +/- 7%) and no plasma cells were seen. The results are discussed in relation to previous reports.

摘要

对患有类风湿性关节炎(RA)且病程较长、正在接受滑膜切除术和关节手术的患者的滑液进行分析发现,滑液中71±15%的单核细胞为淋巴细胞,3±2%为淋巴母细胞,26±15%为单核细胞/巨噬细胞。淋巴细胞群体主要由T细胞组成,72±15%的淋巴细胞OKT11呈阳性。OKT8阳性细胞(48±9%)多于OKT4阳性细胞(32±8%),平均OKT4/OKT8比值为0.69。根据Ia和Tac标志物,很少有淋巴细胞被激活。可见少量B细胞(12±7%),未见浆细胞。结合先前的报告对结果进行了讨论。

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2
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