Department of Chemistry, Federal University of Paraná (UFPR), Curitiba, Brazil.
Department of Plant Biology, University of Campinas (UNICAMP), Campinas, Brazil.
Nat Prod Res. 2022 Nov;36(21):5600-5605. doi: 10.1080/14786419.2021.2022668. Epub 2022 Jan 4.
Three new diterpenoids, demethylfruticuline B (), 20-hydroxyfruticuline B (), and 6-hydroxyisofruticuline A () were isolated from the leaves of Benth, together with five known compounds: fruticuline B (), fruticuline A (), demethylfruticuline A (), heterobetulinic acid (), and maslinic acid (). The known compounds - are being reported for the first time in this species. Compounds and - were tested for antioxidant activity using the ORAC-FL method, and the antioxidant capacity was measured as relative trolox equivalent. All compounds were active, with values of relative trolox equivalent varying between 1.20-2.42. The most active compound was demethylfruticuline B ().
从 Benth 的叶子中分离得到了三种新的二萜类化合物:去甲基野桐素 B ()、20-羟基野桐素 B () 和 6-羟基异野桐素 A (),以及五种已知化合物:野桐素 B ()、野桐素 A ()、去甲基野桐素 A ()、异贝壳杉烯酸 () 和齐墩果酸 ()。已知化合物 - 在该物种中为首次报道。使用 ORAC-FL 法测试了化合物 - 的抗氧化活性,并以相对 Trolox 当量衡量抗氧化能力。所有化合物均具有活性,相对 Trolox 当量值在 1.20-2.42 之间。最活跃的化合物是去甲基野桐素 B ()。