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55 岁以下患者 500 例非骨水泥全膝关节置换术的存活率。

Survivorship of 500 Cementless Total Knee Arthroplasties in Patients Under 55 Years of Age.

机构信息

Primary Joint Unit, Musgrave Park Hospital, Belfast, Northern Ireland, United Kingdom.

出版信息

J Arthroplasty. 2023 May;38(5):820-823. doi: 10.1016/j.arth.2022.10.035. Epub 2022 Oct 27.

Abstract

BACKGROUND

With respect to survivorship following total knee arthroplasty (TKA), joint registries consistently demonstrate higher revision rates for both genders in those aged less than 55 years. The present study analyzed the survivorship of 500 cementless TKAs performed in this age group in a high-volume primary joint unit where cementless TKA has traditionally been used for the majority of patients.

METHODS

This was a retrospective review of 500 consecutive TKAs performed in patients aged less than 55 years between March 1994 and April 2017. The primary outcome measures for the study were survivorship and all-cause revisions. Secondary outcome measures included nonrevision procedures, clinical, functional, and radiological outcomes.

RESULTS

An all-cause survival rate of 98.4% and an aseptic survival rate of 99.2% at a median time of 10.7 years (interquartile range 7.3-14.9, range 0.2-27.7) were found. Four patents were revised for infection, 2 for stiffness, 1 for aseptic loosening of the tibial component, and 1 for a patella that was resurfaced for anterior knee pain. Thirty four patients (6.8%) had a nonrevision procedure with manipulation under anesthetic accounting for 27. On a multivariate analysis, preoperative range of motion and female gender were negatively associated with postoperative range of motion (P < .001 and P = .003, respectively). Sixty seven patients (17.3%) had radioluscent lines and on a multivariate analysis, there were no significant predictors of radiolucent lines.

CONCLUSION

Cementless TKA in the young patient can achieve excellent clinical and functional outcomes. At a median of 10.7 years, aseptic revision rates are exceptionally low at 0.8% for the entire cohort.

摘要

背景

在全膝关节置换术(TKA)后,关节登记处一致显示,55 岁以下的男女患者的翻修率都更高。本研究分析了在一个高容量的初级关节单位中,对 500 例年龄小于 55 岁的行非骨水泥 TKA 的患者的生存情况,该单位传统上对大多数患者使用非骨水泥 TKA。

方法

这是对 1994 年 3 月至 2017 年 4 月期间,500 例年龄小于 55 岁的连续 TKA 患者的回顾性研究。研究的主要终点是生存率和所有原因的翻修。次要终点包括非翻修手术、临床、功能和影像学结果。

结果

中位随访时间为 10.7 年(四分位距 7.3-14.9,范围 0.2-27.7)时,全因生存率为 98.4%,无菌生存率为 99.2%。有 4 例患者因感染、2 例因僵硬、1 例因胫骨组件无菌松动、1 例因髌前疼痛而翻修。34 例患者(6.8%)行非翻修手术,其中 27 例在麻醉下进行了手法复位。多变量分析显示,术前活动范围和女性是与术后活动范围呈负相关的(P<0.001 和 P=0.003)。67 例患者(17.3%)有透亮线,多变量分析显示,透亮线无明显预测因素。

结论

在年轻患者中,非骨水泥 TKA 可获得良好的临床和功能结果。在中位 10.7 年时,整个队列的无菌翻修率为 0.8%,非常低。

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