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非骨水泥型全膝关节置换术的使用趋势:2015年至2021年的全国性分析

Trend of using cementless total knee arthroplasty: a nationwide analysis from 2015 to 2021.

作者信息

Agarwal Amil R, Kuyl Emile-Victor, Gu Alex, Golladay Gregory J, Thakkar Savyasachi C, Siram Gautam, Unger Anthony, Rao Sandesh

机构信息

Department of Orthopaedic Surgery, George Washington University School of Medicine and Health Sciences, Washington, DC, 20052, USA.

Department of Orthopaedic Surgery, Virginia Commonwealth University, Richmond, VA, 23298, USA.

出版信息

Arthroplasty. 2024 Apr 6;6(1):24. doi: 10.1186/s42836-024-00241-7.

Abstract

BACKGROUND

Modern cementless total knee arthroplasty (TKA) fixation has shown comparable long-term outcomes to cemented TKA, but the trend of using cementless TKA remains unclear. This study aimed to investigate the trend of using cementless TKA based on a national database.

METHODS

The patients undergoing cementless TKA between 2015 and 2021 were retrospectively extracted from the PearlDiver (Mariner dataset) Database. The annual percentage of cementless TKA was calculated using the following formula: annual number of cementless TKA/annual number of TKA. The trend of the number of patients undergoing cementless TKA was created according to a compounded annual growth rate (CAGR) calculation of annual percentages. Patient age, comorbidity, region, insurance type, etc., were also investigated. Differences were considered statistically significant at P < 0.05.

RESULTS

Of the 574,848 patients who received TKA, 546,731 (95%) underwent cemented fixation and 28,117 (5%) underwent cementless fixation. From 2015 to 2021, the use of cementless TKA significantly increased by 242% from 3 to 9% (compounded annual growth rate (CAGR): + 20%; P < 0.05). From 2015 to 2021, we observed a CAGR greater than 15% for all age groups (< 50, 50-59, 60-69, 70-74, 75 +), insurance types (cash, commercial, government, Medicare, Medicaid), regions (Midwest, Northeast, South, West), sex (male and female), and certain comorbidities (osteoporosis, diabetes mellitus, tobacco use, underweight (BMI < 18.5), rheumatoid arthritis) (P < 0.05 for all). Patients undergoing TKA with chronic kidney disease, prior fragility fractures, and dementia demonstrated a CAGR of + 9%-13% from 2015 to 2021 (P < 0.05).

CONCLUSION

From 2015 to 2021, the use of cementless TKA saw a dramatic increase in all patient populations. However, there is still no consensus on when to cement and in whom. Clinical practice guidelines are needed to ensure safe and effective use of cementless fixation.

摘要

背景

现代非骨水泥全膝关节置换术(TKA)固定已显示出与骨水泥型TKA相当的长期疗效,但非骨水泥型TKA的使用趋势仍不明确。本研究旨在基于全国性数据库调查非骨水泥型TKA的使用趋势。

方法

从PearlDiver(水手数据集)数据库中回顾性提取2015年至2021年间接受非骨水泥型TKA的患者。非骨水泥型TKA的年度百分比使用以下公式计算:非骨水泥型TKA年度例数/TKA年度例数。根据年度百分比的复合年增长率(CAGR)计算,得出接受非骨水泥型TKA患者数量的趋势。还对患者年龄、合并症、地区、保险类型等进行了调查。P < 0.05时差异具有统计学意义。

结果

在574,848例接受TKA的患者中,546,731例(95%)接受了骨水泥固定,28,117例(5%)接受了非骨水泥固定。从2015年到2021年,非骨水泥型TKA的使用从3%显著增加到9%,增长了242%(复合年增长率(CAGR):+20%;P < 0.05)。从2015年到2021年,我们观察到所有年龄组(<50岁、50 - 59岁、60 - 69岁、70 - 74岁、75岁及以上)、保险类型(现金、商业、政府、医疗保险、医疗补助)、地区(中西部、东北部、南部、西部)、性别(男性和女性)以及某些合并症(骨质疏松症、糖尿病、吸烟、体重过轻(BMI < 18.5)、类风湿性关节炎)的CAGR均大于15%(所有P < 0.05)。2015年至2021年间,患有慢性肾病、既往脆性骨折和痴呆症的TKA患者的CAGR为+9% - 13%(P < 0.05)。

结论

从2015年到2021年,所有患者群体中非骨水泥型TKA的使用都有显著增加。然而,对于何时使用骨水泥以及哪些患者适用仍未达成共识。需要临床实践指南来确保非骨水泥固定的安全有效使用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3c8/10998332/2956c416b6ed/42836_2024_241_Fig1_HTML.jpg

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