Angello D A, Wilson R A, Palac R T
Am J Cardiol. 1987 Sep 1;60(7):528-33. doi: 10.1016/0002-9149(87)90299-2.
To determine whether eating a high-carbohydrate meal between initial and delayed postexercise thallium-201 (Tl-201) imaging affects detection of Tl-201 redistribution during exercise stress testing, 16 patients with stable angina performed 2 Tl-201 treadmill exercise stress tests within a 14-day interval. Immediately after initial postexercise imaging, patients either drank a commercially available instant breakfast preparation for the intervention test or drank an equivalent volume of water for the control test. Comparable exercise workloads were achieved by exercising patients to the same heart rate for both tests. The order of the 2 (intervention and control) tests were randomized. All patients had at least 1 region of Tl-201 myocardial redistribution on either their eating or control test scans, although only 7 of the 16 had positive treadmill exercise test responses. Forty-six regions showing Tl-201 myocardial redistribution were identified in all 144 regions examined. Significantly more of these regions were identified on control test scans than on eating test scans: 11 of 46 on both test scans, 6 of 46 only on eating test scans and 29 of 46 only on control scans (p less than 0.001). Consistent with results of the quantitative regional analysis, the percentage of Tl-201 clearance over 4 hours in the 46 Tl-201 myocardial redistribution regions was 39 +/- 8% for the eating tests and 29 +/- 8% for control tests (mean +/- standard deviation, p less than 0.003). In 4 patients diagnosis of transient ischemia would have been missed because their 14 Tl-201 myocardial redistribution regions were detected only on the control test scans.(ABSTRACT TRUNCATED AT 250 WORDS)
为了确定在运动后早期和延迟的铊-201（Tl-201）成像之间进食高碳水化合物餐是否会影响运动负荷试验期间Tl-201再分布的检测，16例稳定型心绞痛患者在14天内进行了2次Tl-201平板运动负荷试验。在运动后早期成像后，患者立即饮用市售速溶早餐制剂进行干预试验，或饮用等量的水进行对照试验。通过使患者在两次试验中达到相同心率来实现可比的运动负荷。这两项（干预和对照）试验的顺序是随机的。所有患者在进食或对照试验扫描中至少有1个Tl-201心肌再分布区域，尽管16例患者中只有7例平板运动试验反应阳性。在所有检查的144个区域中，共识别出46个显示Tl-201心肌再分布的区域。对照试验扫描中识别出的这些区域明显多于进食试验扫描：46个区域中，两项试验扫描均有11个，仅进食试验扫描有6个，仅对照扫描有29个（p<0.001）。与定量区域分析结果一致，46个Tl-201心肌再分布区域在进食试验中4小时内Tl-20清除率为39±8%，对照试验为29±8%（平均值±标准差，p<0.003）。4例患者因仅在对照试验扫描中检测到其14个Tl-201心肌再分布区域而漏诊短暂性心肌缺血。（摘要截短至250字）
