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医疗补助扩大计划与妇科癌症女性术后死亡率:一项差分分析。

Medicaid Expansion and Postoperative Mortality in Women with Gynecologic Cancer: A Difference-in-Difference Analysis.

机构信息

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 1362, Houston, TX, 77030, USA.

Department of Health Services Research, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

出版信息

Ann Surg Oncol. 2023 Mar;30(3):1508-1519. doi: 10.1245/s10434-022-12663-1. Epub 2022 Oct 30.

Abstract

BACKGROUND

The association between Medicaid expansion and postoperative mortality after surgery for gynecologic cancer is unknown. Our objective was to compare 30- and 90-day postoperative mortality after gynecologic cancer surgery before and after 2014 in states that did and did not expand Medicaid.

METHODS

We searched the National Cancer Database for women aged 40-64 years old between 2010 and 2016 who underwent surgery for a primary gynecologic malignancy. We used pre/post and quasi-experimental difference-in-difference (DID) multivariable logistic regressions to evaluate mortality pre-2014 (2010-2013) and post-2014 (2014-2016) for states that did and did not expand Medicaid in January 2014. We completed univariable logistic regressions for covariates of interest.

RESULTS

Among 169,731 women, 30-day postoperative mortality in expansion states after 2014 significantly decreased for endometrial cancer (odds ratio [OR] 0.42, 95% confidence interval [CI] 0.26-0.67) and ovarian cancer (OR 0.67, 95% CI 0.46-0.99) and increased for cervical cancer (OR 3.82, 95% CI 1.12-13.01). Compared with non-expansion states, expansion states had improved 30-day postoperative mortality for endometrial cancer after 2014 (DID OR 0.54, 95% CI 0.31-0.96). Univariable analysis demonstrated improved 30-day postoperative mortality for Black women with endometrial cancer in expansion states (DID OR 0.22, 95% CI 0.05-0.95). There was improved 90-day postoperative mortality for endometrial cancer in expansion states (OR 0.66, 95% CI 0.50-0.85), and improved 90-day postoperative mortality for Midwestern women with ovarian cancer in expansion states on univariable analysis (DID OR 0.48, 95% CI 0.26-0.91).

CONCLUSIONS

State Medicaid legislation was associated with improved postoperative survival in women with endometrial cancer and subgroups of women with endometrial and ovarian cancer.

摘要

背景

医疗补助计划(Medicaid)扩围与妇科癌症手术后的 30 天和 90 天死亡率之间的关联尚不清楚。我们的目的是比较在没有和有扩围医疗补助计划的州,2014 年前和 2014 年后妇科癌症手术后 30 天和 90 天的术后死亡率。

方法

我们在国家癌症数据库中检索了 2010 年至 2016 年间年龄在 40-64 岁之间、患有原发性妇科恶性肿瘤的女性数据。我们使用前后和准实验性差值(DID)多变量逻辑回归来评估 2014 年前(2010-2013 年)和 2014 年后(2014-2016 年)在 2014 年 1 月有和没有扩围医疗补助计划的州的死亡率。我们完成了感兴趣的协变量的单变量逻辑回归。

结果

在 169731 名女性中,2014 年后扩围州的子宫内膜癌(比值比 [OR] 0.42,95%置信区间 [CI] 0.26-0.67)和卵巢癌(OR 0.67,95%CI 0.46-0.99)的 30 天术后死亡率显著下降,而宫颈癌(OR 3.82,95%CI 1.12-13.01)的死亡率则上升。与非扩围州相比,扩围州的子宫内膜癌患者的 30 天术后死亡率在 2014 年后有所改善(DID OR 0.54,95%CI 0.31-0.96)。单变量分析显示,扩围州的黑人子宫内膜癌患者的 30 天术后死亡率有所改善(DID OR 0.22,95%CI 0.05-0.95)。扩围州的子宫内膜癌患者的 90 天术后死亡率有所改善(OR 0.66,95%CI 0.50-0.85),且在单变量分析中,扩围州的中西部卵巢癌患者的 90 天术后死亡率也有所改善(DID OR 0.48,95%CI 0.26-0.91)。

结论

州医疗补助立法与子宫内膜癌和子宫内膜癌及卵巢癌亚组女性的术后生存改善有关。

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