Eckhauser M L, Dokler M, Imbembo A L
Am J Gastroenterol. 1987 Sep;82(9):865-70.
Three patients are presented as illustrative examples of severe necrotizing pancreatitis associated with diuretic therapy. The presumed initiating factor was use of a benzothiadiazine (chlorothiazide, hydrochlorothiazide) or phthalimidine (chlorthalidone) diuretic to control hypertension, after the exclusion of other etiologies. We present these illustrative cases and a collective review, emphasizing that pancreatitis associated with these widely prescribed medications can be fatal and may be more common that previously thought.
本文介绍了三例严重坏死性胰腺炎与利尿治疗相关的病例，作为说明性示例。在排除其他病因后，推测引发因素是使用苯并噻二嗪类（氯噻嗪、氢氯噻嗪）或邻苯二甲酰亚胺类（氯噻酮）利尿剂来控制高血压。我们展示这些说明性病例并进行综合回顾，强调与这些广泛使用的药物相关的胰腺炎可能是致命的，而且可能比之前认为的更为常见。
