Manabe T, Inagaki Y, Nakagawa S, Miyoshi K, Ueki H
Am J Dermatopathol. 1987 Aug;9(4):301-7. doi: 10.1097/00000372-198708000-00003.
Ripple pigmentary lesions of the neck were observed in 12 patients with atopic dermatitis. Biopsy specimens from three cases revealed no amyloid substances. From the review of cases with either atopic dermatitis or ripple pigmentation seen in our hospital, it was concluded that ripple pigmentation of the neck was always associated with atopic dermatitis and appeared in 1.7% of all 751 patients with atopic dermatitis. It is suggested that ripple pigmentation is not necessarily specific or diagnostic of amyloidosis, as is generally believed. Possible relationships involving ripple pigmentation, atopic dermatitis, and macular amyloidosis are also discussed.
在12例特应性皮炎患者中观察到颈部有波纹状色素沉着病变。3例患者的活检标本未发现淀粉样物质。通过回顾我院收治的特应性皮炎或有波纹状色素沉着的病例，得出结论：颈部的波纹状色素沉着总是与特应性皮炎相关，在751例特应性皮炎患者中占1.7%。提示波纹状色素沉着并不像普遍认为的那样一定是淀粉样变性的特异性表现或诊断依据。还讨论了波纹状色素沉着、特应性皮炎和斑状淀粉样变性之间可能的关系。
