Department of Dermatology and Cutaneous Biology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA.
Laser & Skin Surgery Center of New York, New York, NY;
Skinmed. 2022 Oct 31;20(5):350-352. eCollection 2022.
Melasma is a chronic cutaneous condition that not only affects the appearance of patients but also has an immense psychosocial impact on patient quality of life. Although many treatment options are currently available, there is no single universal treatment regimen that works for all patients. Significant attention has been recently focused on the development and use of topical treatments that can lighten the dark patches associated with melasma. One such ingredient that has received growing attention in recent years is cysteamine. It works through several mechanisms to influence the melanogenesis pathway. This commentary reviews the information on this topical ingredient and offers relevant clinical insights.
黄褐斑是一种慢性皮肤疾病，不仅影响患者的外观，而且对患者的生活质量也有巨大的心理社会影响。尽管目前有许多治疗选择，但没有一种单一的通用治疗方案适用于所有患者。近年来，人们对外用治疗药物的开发和使用给予了极大的关注，这些药物可以减轻与黄褐斑相关的黑斑。近年来，半胱胺作为一种备受关注的成分，其作用机制涉及多个方面，从而影响黑素生成途径。本文评论了这种局部用药物的相关信息，并提供了相关的临床见解。
