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经皮硬膜外球囊神经成形术:当前证据的叙述性综述

Percutaneous epidural balloon neuroplasty: a narrative review of current evidence.

作者信息

Kim Doo-Hwan, Shin Jin-Woo, Choi Seong-Soo

机构信息

Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

出版信息

Anesth Pain Med (Seoul). 2022 Oct;17(4):361-370. doi: 10.17085/apm.22237. Epub 2022 Oct 26.

Abstract

Percutaneous epidural balloon neuroplasty (PEBN) can be used to perform balloon decompression combined with percutaneous epidural neuroplasty (PEN), leading to significant pain relief and functional improvement in patients with lumbar spinal stenosis. Several studies have demonstrated the effectiveness of PEBN and supported its relatively long-term outcomes (at least 6 months, sustained for up to 12 months). Balloon neuroplasty appears to be superior to conventional PEN. Moreover, it has been shown to be effective in patients unresponsive to conventional PEN or in those with post lumbar surgery syndrome. In addition, balloon neuroplasty achieved successful outcomes regardless of the approach used, such as retrodiscal, transforaminal, contralateral interlaminar, or caudal. Chronic lumbar radicular pain without back pain, neurogenic claudication, and minimal neuropathic component were favorable predictors of successful PEBN from a symptomatic perspective. A short duration of pain after lumbar surgery, lumbar foraminal stenosis caused primarily by degenerative disc, mild foraminal stenosis, and perineural adhesion by degenerative discs were associated with successful outcomes of PEBN from pathological aspects. Ballooning ≥ 50% of the target sites and complete contrast dispersion after ballooning seemed to be crucial for successful outcomes from a technical perspective. In addition, PEBN was effective regardless of the accompanying redundant nerve roots or a mild degree of spondylolisthesis. Studies on balloon neuroplasty have reported occasional minor and self-limiting complications; however, no PEBN-related significant complications have been reported. Given the present evidence, balloon neuroplasty appears to be a safe and effective procedure with minimal complications for the treatment of lumbar spinal stenosis.

摘要

经皮硬膜外球囊神经成形术(PEBN)可用于进行球囊减压并结合经皮硬膜外神经成形术(PEN),从而使腰椎管狭窄症患者的疼痛得到显著缓解且功能得到改善。多项研究已证实PEBN的有效性,并支持其相对长期的疗效(至少6个月,可持续长达12个月)。球囊神经成形术似乎优于传统的PEN。此外,已证明其对传统PEN无反应的患者或患有腰椎手术后综合征的患者有效。此外,无论采用何种入路,如椎间盘后入路、椎间孔入路、对侧椎板间入路或尾侧入路,球囊神经成形术均取得了成功的结果。从症状角度来看,无背痛的慢性腰神经根性疼痛、神经源性间歇性跛行以及最小的神经病变成分是PEBN成功的有利预测因素。从病理方面来看,腰椎手术后疼痛持续时间短、主要由退变椎间盘引起的腰椎椎间孔狭窄、轻度椎间孔狭窄以及退变椎间盘引起的神经周围粘连与PEBN的成功结果相关。从技术角度来看,球囊扩张目标部位≥50%以及球囊扩张后造影剂完全弥散似乎是成功结果的关键。此外,无论是否伴有多余神经根或轻度椎体滑脱,PEBN均有效。关于球囊神经成形术的研究报告了偶尔出现的轻微且自限性的并发症;然而,尚未报告与PEBN相关的重大并发症。鉴于目前的证据,球囊神经成形术似乎是一种安全有效的手术,治疗腰椎管狭窄症的并发症极少。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbcb/9663944/21d28768ebeb/apm-22237f1.jpg

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