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后路经皮硬膜外粘连松解术联合 WHIP 导管治疗腰椎神经根病的疗效分析:一项回顾性研究。

Analysis of the efficacy of retrodiscal approach percutaneous epidural adhesiolysis with WHIP catheter® in patients with lumbar radiculopathy: A retrospective study.

机构信息

Department of Anesthesiology and Pain Medicine, Korea University Anam Hospital, Seoul, Korea.

Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.

出版信息

Medicine (Baltimore). 2024 Jun 7;103(23):e38452. doi: 10.1097/MD.0000000000038452.

Abstract

Percutaneous epidural adhesiolysis (PEA) is an effective treatment for patients with lumbar radiculopathy unresponsive to single steroid injections. Various approaches and instruments have been developed to access these lesions. This study aimed to evaluate the utility of a retrodiscal approach for epidural adhesiolysis using a WHIP catheter®. This retrospective study was conducted at Bundang Seoul National University Hospital, reviewing cases from January to December 2022. Forty-seven patients diagnosed with lumbar radiculopathy, aged 20 to 80 years, who underwent PEA with the WHIP catheter® were included. Outcomes assessed Numeric Rating Scale (NRS) for pain, Patients' Global Impression of Change (PGIC) scores, and the incidence of procedure-related complications. Follow-up evaluations occurred at 1, 3, and 6 months post-procedure. Among 47 patients, 41 completed the study, showing significant pain reduction at all follow-up points: 1 month (N = 41, 1.32 ± 1.68, P < .001), 3 months (N = 31, 1.90 ± 2.14, P < .001), and 6 months (N = 30, 2.50 ± 2.30, P < .001). PGIC scores indicated that 40% of the patients reported substantial improvement at one-month post-procedure. The complications were minimal, with only one case of intradiscal injection and 2 cases of vascular uptake. The retrodiscal approach PEA using the WHIP catheter® demonstrated significant efficacy in pain reduction with minimal safety concerns for patients with lumbar radiculopathy. These findings suggest that this procedure is a viable option for patients who are unresponsive to conservative treatment. However, the retrospective nature of this study and its small sample size necessitate further prospective controlled studies to confirm our results and establish long-term outcomes.

摘要

经皮硬膜外粘连松解术(PEA)是治疗对单次类固醇注射无反应的腰椎神经根病患者的有效方法。已经开发了各种方法和器械来接近这些病变。本研究旨在评估使用 WHIP 导管®进行经椎间盘后路入路硬膜外粘连松解术的效用。这是一项在盆唐首尔国立大学医院进行的回顾性研究,对 2022 年 1 月至 12 月期间的病例进行了回顾。纳入了 47 名年龄在 20 至 80 岁之间、接受 WHIP 导管®行 PEA 的腰椎神经根病患者。评估的结果包括疼痛的数字评定量表(NRS)、患者整体印象变化(PGIC)评分和与手术相关的并发症发生率。在术后 1、3 和 6 个月进行随访评估。在 47 名患者中,41 名完成了研究,所有随访点的疼痛均明显减轻:1 个月(N=41,1.32±1.68,P<0.001)、3 个月(N=31,1.90±2.14,P<0.001)和 6 个月(N=30,2.50±2.30,P<0.001)。PGIC 评分表明,术后 1 个月时,40%的患者报告有显著改善。并发症很少,只有 1 例椎间盘内注射和 2 例血管摄取。使用 WHIP 导管®进行经椎间盘后路入路 PEA 在减轻疼痛方面具有显著疗效,同时对腰椎神经根病患者的安全性问题较小。这些发现表明,对于对保守治疗无反应的患者,该手术是一种可行的选择。然而,由于本研究为回顾性且样本量较小,因此需要进一步的前瞻性对照研究来证实我们的结果并确定长期结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/853b/11155536/aff0f16245c8/medi-103-e38452-g001.jpg

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