对肺癌的补充免疫。

Complement-ary immunity to lung cancer.

机构信息

Science Signaling, AAAS, Washington, DC 20005, USA. Email:

出版信息

Sci Signal. 2022 Nov;15(758):eadf5050. doi: 10.1126/scisignal.adf5050. Epub 2022 Nov 1.

DOI:10.1126/scisignal.adf5050

PMID:36318620

Abstract

Restoring complement signaling in lung cancer enhances the efficacy of immunotherapy in mouse models.

摘要

恢复肺癌中的补体信号转导可增强免疫疗法在小鼠模型中的疗效。

相似文献

Complement-ary immunity to lung cancer.

Sci Signal. 2022 Nov;15(758):eadf5050. doi: 10.1126/scisignal.adf5050. Epub 2022 Nov 1.

Autocrine Complement Inhibits IL10-Dependent T-cell-Mediated Antitumor Immunity to Promote Tumor Progression.

Cancer Discov. 2016 Sep;6(9):1022-35. doi: 10.1158/2159-8290.CD-15-1412. Epub 2016 Jun 13.

ILT4 inhibition prevents TAM- and dysfunctional T cell-mediated immunosuppression and enhances the efficacy of anti-PD-L1 therapy in NSCLC with EGFR activation.

Theranostics. 2021 Jan 19;11(7):3392-3416. doi: 10.7150/thno.52435. eCollection 2021.

Complement system in lung disease.

Am J Respir Cell Mol Biol. 2014 Oct;51(4):467-73. doi: 10.1165/rcmb.2013-0485TR.

Complement System: An Immunotherapy Target in Colorectal Cancer.

Front Immunol. 2022 Jan 31;13:810993. doi: 10.3389/fimmu.2022.810993. eCollection 2022.

Dichotomy of complement system: Tumorigenesis or destruction.

Immunol Lett. 2020 Jul;223:89-96. doi: 10.1016/j.imlet.2020.04.013. Epub 2020 Apr 22.

Unwelcome complement.

Cancer Res. 2009 Aug 15;69(16):6367-70. doi: 10.1158/0008-5472.CAN-09-1918. Epub 2009 Aug 4.

Complementing T-cell Function: An Inhibitory Role of the Complement System in T-cell-Mediated Antitumor Immunity.

Cancer Discov. 2016 Sep;6(9):953-5. doi: 10.1158/2159-8290.CD-16-0698.

Complement function in mAb-mediated cancer immunotherapy.

Trends Immunol. 2004 Mar;25(3):158-64. doi: 10.1016/j.it.2004.01.008.

Immunotherapy combined with primary resection of murine fibrosarcoma: correlation of immunological status of the host with prevention of metastases.

Ann Surg. 1972 Oct;176(4):544-53. doi: 10.1097/00000658-197210000-00013.

引用本文的文献

Anoikis classification of lung squamous cell carcinoma reveals correlation with clinical prognosis and immune characteristics.

Ann Med. 2025 Dec;57(1):2514944. doi: 10.1080/07853890.2025.2514944. Epub 2025 Jun 14.

Activation of the complement system sensitizes immune checkpoint blockade.

J Natl Cancer Cent. 2022 Dec 23;3(1):4-6. doi: 10.1016/j.jncc.2022.11.005. eCollection 2023 Mar.

Machine-learning and combined analysis of single-cell and bulk-RNA sequencing identified a DC gene signature to predict prognosis and immunotherapy response for patients with lung adenocarcinoma.

J Cancer Res Clin Oncol. 2023 Nov;149(15):13553-13574. doi: 10.1007/s00432-023-05151-w. Epub 2023 Jul 28.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

对肺癌的补充免疫。

Complement-ary immunity to lung cancer.

机构信息

出版信息

相似文献

引用本文的文献

文献AI研究员

用中文搜PubMed

文档翻译

Suppr 超能文献

相似文献

引用本文的文献

对肺癌的补充免疫。

Complement-ary immunity to lung cancer.

机构信息

出版信息