Khaĭtovich A B, Ved'mina E A
Antibiot Med Biotekhnol. 1987 Jun;32(6):446-9.
Sensitivity of vibrios and aeromonads to vibriostatic O129 (2,4-diamino-6,7-diisopropyl pteridine) was studied. The vibrios and aeromonads were isolated in the USSR. The tests were performed with disks made in the USSR and Great Britain. The content of the drug in the disks was 10 and 150 micrograms. It was shown that V. cholerae O1 V. cholerae not O1 and V. albensis were highly sensitive to vibriostatic O129 and produced no growth in the presence of either low or high concentrations of the drug. Halophilic vibrios and 26.3 per cent of the aeromonads resistant to low concentrations of the drug were less sensitive to the vibriostatic. The aeromonads and plesiomonads were resistant to the drug. The reaction to vibriostatic O129 was found to be one of the biological features of vibrios and aeromonads which can be used for differentiation of genera Vibrio and Aeromonas and within genus Vibrio as a taxonomic criterion.
研究了弧菌和气单胞菌对弧菌抑制剂O129（2,4 - 二氨基 - 6,7 - 二异丙基蝶啶）的敏感性。这些弧菌和气单胞菌是在苏联分离得到的。测试使用了苏联和英国生产的滤纸片。滤纸片中药物含量分别为10微克和150微克。结果表明，霍乱弧菌O1、非O1霍乱弧菌和阿尔贝尼弧菌对弧菌抑制剂O129高度敏感，在低浓度或高浓度药物存在时均不生长。嗜盐弧菌和26.3%对低浓度药物有抗性的气单胞菌对弧菌抑制剂的敏感性较低。气单胞菌和邻单胞菌对该药物有抗性。发现对弧菌抑制剂O129的反应是弧菌和气单胞菌的生物学特征之一，可用于区分弧菌属和气单胞菌属，以及在弧菌属内作为分类标准。
