Gundogan Ersin, Kayaalp Cuneyt, Alınak Gundogan Gokcen, Sumer Fatih
Department of General Surgery-Kayseri State Hospital, Health Science University, Kayseri, Turkey.
Department of Gastrointestinal Surgery, Inonu University, Malatya, Turkey.
Updates Surg. 2023 Jan;75(1):197-203. doi: 10.1007/s13304-022-01412-4. Epub 2022 Nov 1.
Natural orifice surgery has been used with increasing frequency in colon surgeries since the early 2000's. Our aim was to examine the patients retrospectively who underwent Natural Orifice Specimen Excision (NOSE) following laparoscopic colorectal resection. A total of 102 patients 2013 and 2018 were evaluated. The demographic characteristics, intra-operative and post-operative findings, pathology results, pain, incontinence, sexual dysfunction and cosmetic scores were examined. Mean age was 57.0 ± 14 and 52 of them (51%) were female. Specimen extraction was transanal in 72 (70%) (eventration technique in 10 patients) and transvaginal in the remaining 30 patients. The mean operating time was 272 ± 108 (median 240, range 120-540) minutes, and the mean blood loss was 92 ± 87 ml (median 54, range 5-400). The mean hospital stay was 7.0 ± 4.7 days (median 6, range 3-30). The main pain scores (visual analog score) on days 1-2-3 were 3.9 ± 2.0 (median 4, range 1-9), 3.1 ± 1.7 (median 3, range 0-8), 1.9 ± 1.5 (median 1.5, range 0-7), respectively. The mean cosmetic scores were 9.1 ± 1.5 (median 10, range 3-10). The median Wexner Incontinence score was 0 (0-9). Hospital mortality was 1% and unrelated with the NOSE. The 5-year overall survival and disease-free survival rates for cancer patients were 77.2-63.3%, respectively. NOSE has advantages in laparoscopic colorectal resections. It increases patient comfort and decreases incision related complications. CLINICAL TRIALS: www.clinicaltrials.gov (NCT04394988).
自21世纪初以来,自然腔道手术在结肠手术中的应用频率越来越高。我们的目的是对接受腹腔镜结直肠切除术后进行自然腔道标本切除术(NOSE)的患者进行回顾性研究。对2013年至2018年期间的102例患者进行了评估。检查了患者的人口统计学特征、术中及术后结果、病理结果、疼痛、失禁、性功能和美容评分。平均年龄为57.0±14岁,其中52例(51%)为女性。72例(70%)经肛门取出标本(10例采用外翻技术),其余30例经阴道取出标本。平均手术时间为272±108(中位数240,范围120 - 540)分钟,平均失血量为92±87 ml(中位数54,范围5 - 400)。平均住院时间为7.0±4.7天(中位数6,范围3 - 30)。第1、2、3天的主要疼痛评分(视觉模拟评分)分别为3.9±2.0(中位数4,范围1 - 9)、3.1±1.7(中位数3,范围0 - 8)、1.9±1.5(中位数1.5,范围0 - 7)。平均美容评分为9.1±1.5(中位数10,范围3 - 10)。Wexner失禁评分中位数为0(0 - 9)。医院死亡率为1%,与NOSE无关。癌症患者的5年总生存率和无病生存率分别为77.2% - 63.3%。NOSE在腹腔镜结直肠切除术中具有优势。它提高了患者的舒适度并减少了切口相关并发症。临床试验:www.clinicaltrials.gov(NCT043