Boomgaardt Jacob, Dastan Kovosh, Chan Tiffany, Shilling Ashley, Abd-Elsayed Alaa, Kohan Lynn
Department of Physical Medicine and Rehabilitation, University of Virginia, Charlottesville, VA, USA.
Department of Anesthesiology, University of Virginia, Charlottesville, VA, USA.
J Pain Res. 2022 Oct 26;15:3349-3367. doi: 10.2147/JPR.S355278. eCollection 2022.
Phantom limb pain (PLP) is a common condition that occurs following both upper and lower limb amputation. First recognized and described in 1551 by Ambroise Pare, research into its underlying pathology and effective treatments remains a very active and growing field. To date, however, there is little consensus regarding the optimal management of phantom limb pain. With few large well-designed clinical trials of which to make treatment recommendations, as well as significant heterogeneity in clinical response to available treatments, the management of PLP remains challenging. Below we summarize the current state of knowledge in the field, as well as propose an algorithm for the approach to the treatment of PLP.
幻肢痛（PLP）是一种常见病症，发生于上肢或下肢截肢之后。1551年由安布鲁瓦兹·帕雷首次发现并描述，对其潜在病理和有效治疗方法的研究仍是一个非常活跃且不断发展的领域。然而，迄今为止，关于幻肢痛的最佳管理几乎没有共识。由于可供做出治疗推荐的大型精心设计的临床试验很少，以及对现有治疗方法的临床反应存在显著异质性，幻肢痛的管理仍然具有挑战性。以下我们总结该领域的当前知识状态，并提出一种幻肢痛治疗方法的算法。
