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非小细胞肺癌患者术后肺康复的最新进展(综述)。

Recent advances in postoperative pulmonary rehabilitation of patients with non‑small cell lung cancer (Review).

机构信息

Department of Anaesthesia, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian 362000, P.R. China.

Centre of Neurological and Metabolic Research, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian 362000, P.R. China.

出版信息

Int J Oncol. 2022 Dec;61(6). doi: 10.3892/ijo.2022.5446. Epub 2022 Nov 2.

Abstract

Non‑small cell lung cancer (NSCLC) accounts for ~85% of lung cancer cases and has high morbidity and mortality rates. Over the past decade, treatment strategies for NSCLC have progressed rapidly, particularly with the increasing use of screening programs, leading to improvements in the initial diagnosis and treatment of early‑stage and preinvasive tumors. Surgical intervention remains the primary treatment for early‑stage NSCLC. Thoracoscopic lobectomy has become the main treatment for early‑stage NSCLC, as it results in less postoperative bleeding and pain and fewer complications. However, the complication rate for thoracoscopic lobectomy due to sputum retention and weakened respiratory muscle strength remains as high as 19‑59%. Treating NSCLC remains challenging in terms of postoperative pulmonary rehabilitation. In the present review, recent advances in postoperative pulmonary rehabilitation for patients with NSCLC were presented in order to assist researchers in developing improved treatments to enhance postoperative pulmonary rehabilitation for such patients.

摘要

非小细胞肺癌(NSCLC)约占肺癌病例的 85%,具有高发病率和死亡率。在过去的十年中,NSCLC 的治疗策略取得了快速进展,特别是随着筛查计划的广泛应用,使得早期和侵袭前肿瘤的初始诊断和治疗得到了改善。手术干预仍然是早期 NSCLC 的主要治疗方法。电视辅助胸腔镜肺叶切除术已成为早期 NSCLC 的主要治疗方法,因为它可减少术后出血和疼痛,且并发症更少。然而,由于痰液潴留和呼吸肌无力导致的电视辅助胸腔镜肺叶切除术的并发症发生率仍高达 19%-59%。对于术后肺康复,治疗 NSCLC 仍然具有挑战性。在本综述中,介绍了 NSCLC 患者术后肺康复的最新进展,以帮助研究人员开发出更好的治疗方法,从而增强此类患者的术后肺康复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/932a/9635865/1810e0950e32/IJO-61-6-05446-g00.jpg

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