保加利亚猪肝渗出液中戊型肝炎病毒感染的血清学检测：血清流行病学调查的一种替代方法

Serological Searching for Hepatitis E Virus Infection Among Pig Liver Transudate from Bulgaria: An Alternative Method for Seroepidemiological Survey.

作者信息

Tsachev Ilia, Baymakova Magdalena, Bangieva Desislava, Khezzani Bachir, Kundurzhiev Todor, Valeva Betina, Pepovich Roman

机构信息

Department of Microbiology, Infectious and Parasitic Diseases, Faculty of Veterinary Medicine, Trakia University, Stara Zagora, Bulgaria.

Department of Infectious Diseases, Military Medical Academy, Sofia, Bulgaria.

出版信息

Vector Borne Zoonotic Dis. 2022 Dec;22(12):596-599. doi: 10.1089/vbz.2022.0041. Epub 2022 Nov 2.

DOI:10.1089/vbz.2022.0041

PMID:36322875

Abstract

The aim of this research was to perform a seroepidemiological survey of hepatitis E virus (HEV) by an alternative method-serological establishment of the virus from pig liver transudate. This is the first such research in Bulgaria. Moreover, no studies have been conducted on HEV in pig liver in our country. A total of 90 liver samples from healthy pigs were collected from slaughterhouses in three parts of the country (Sofia, Lovech, and Stara Zagora districts). An equal number of samples ( = 30) were obtained from each district. The overall HEV seropositivity was 67.7% of all 90 tested pig liver transudate samples; in Sofia district 20.0%, in Lovech district 90.0%, and in Stara Zagora district 93.3%. These data are similar to our previous serological studies for HEV in serum samples from industrial pigs, wild boars, and East Balkan swine. In this regard, testing the liver transudate could be a fine alternative method for seroepidemiological survey on HEV in swine.

摘要

本研究的目的是通过一种替代方法——从猪肝渗出液中进行病毒血清学鉴定，对戊型肝炎病毒（HEV）进行血清流行病学调查。这是保加利亚首次开展此类研究。此外，我国尚未对猪肝中的戊型肝炎病毒进行过研究。从该国三个地区（索非亚、洛维奇和旧扎戈拉地区）的屠宰场收集了90份健康猪的肝脏样本。每个地区获得的样本数量相等（=30）。在所有90份检测的猪肝渗出液样本中，戊型肝炎病毒血清阳性率总体为67.7%；在索非亚地区为20.0%，在洛维奇地区为90.0%，在旧扎戈拉地区为93.3%。这些数据与我们之前对工业猪、野猪和东巴尔干猪血清样本中戊型肝炎病毒的血清学研究结果相似。在这方面，检测肝脏渗出液可能是猪戊型肝炎病毒血清流行病学调查的一种很好的替代方法。