孤立性外直肌大B细胞淋巴瘤：1例罕见病例报告并文献复习
Isolated lateral rectus muscle large B cell lymphoma: A rare case report and review of the literature.
作者信息
Rafizadeh Seyed Mohsen, Nozarian Zohreh, Sonbolestan Seyed Ali
机构信息
Department of Oculo-facial Plastic and Reconstructive Surgery, Farabi Hospital, Eye Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Department of Pathology, Farabi Hospital, Tehran University of Medical Sciences, Tehran, Iran.
出版信息
Am J Ophthalmol Case Rep. 2022 Oct 26;28:101736. doi: 10.1016/j.ajoc.2022.101736. eCollection 2022 Dec.
PURPOSE
To report a 65-year-old male patient with primary lateral rectus large B cell lymphoma.
OBSERVATIONS
The patient had been referred because of progressive proptosis and limitation of ductions, especially abduction (ortho position at primary gaze) and conjunctival injection. Computerized tomography of the orbit and paranasal sinuses depicted a massive lateral rectus muscle enlargement without any other orbital involvement. Lateral orbitotomy and lateral rectus belly incisional biopsy was done, and histopathologic and immunohistochemical staining and systemic evaluations revealed the diagnosis of primary orbital large B-cell lymphoma.
CONCLUSIONS AND IMPORTANCE
This case indicated that, though rare, extraocular muscle enlargement could be the main finding of primary orbital lymphoma. Large B-cell lymphoma could involve only the orbital tissues, although it is more prevalent with systemic involvement.
目的
报告一名65岁男性原发性外直肌大B细胞淋巴瘤患者。
观察结果
该患者因进行性眼球突出、眼球运动受限，尤其是外展受限（第一眼位时正位）和结膜充血而就诊。眼眶和鼻窦的计算机断层扫描显示外直肌明显增粗，无其他眼眶受累情况。行外侧眶切开术及外直肌肌腹切开活检，组织病理学、免疫组织化学染色及全身评估确诊为原发性眼眶大B细胞淋巴瘤。
结论及意义
该病例表明，尽管罕见，但眼外肌增粗可能是原发性眼眶淋巴瘤的主要表现。大B细胞淋巴瘤可能仅累及眼眶组织，尽管其更常见于伴有全身受累的情况。
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