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一例继发于眼外肌淋巴瘤的压迫性视神经病变

A Case of Compressive Optic Neuropathy Secondary to Lymphoma of the Extraocular Muscles.

作者信息

Kitaguchi Yoshiyuki, Watanabe Atsushi, Nishida Kohji

机构信息

Department of Ophthalmology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.

出版信息

Neuroophthalmology. 2019 May 2;44(5):327-331. doi: 10.1080/01658107.2019.1603242.

DOI:10.1080/01658107.2019.1603242
PMID:33012923
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7518329/
Abstract

Compressive optic neuropathy is an urgent condition that may lead to blindness. We report a rare case of compressive optic neuropathy secondary to lymphoma of the extraocular muscles in which the vision was successfully rescued. A 67-year-old man presented with visual acuity of hand motion in the right eye for 1 month. Magnetic resonance imaging demonstrated enlargement of the medial and inferior rectus muscles with their tendons. Tendon enlargement, which is uncommon as Graves' orbitopathy, motivated us to perform a biopsy. Intravenous steroids following biopsy and chemotherapy after definitive diagnosis allowed for recovery of vision. Clinicians should be aware that enlarged extraocular muscles due to lymphoma can cause compressive optic neuropathy.

摘要

压迫性视神经病变是一种可能导致失明的急症。我们报告了一例罕见的因眼外肌淋巴瘤继发的压迫性视神经病变,其视力成功得到挽救。一名67岁男性,右眼视力为手动,持续1个月。磁共振成像显示内直肌和下直肌及其肌腱增粗。肌腱增粗在格雷夫斯眼病中并不常见,这促使我们进行活检。活检后静脉注射类固醇以及确诊后进行化疗使视力得以恢复。临床医生应意识到,淋巴瘤导致的眼外肌增粗可引起压迫性视神经病变。

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Can J Ophthalmol. 2019 Apr;54(2):e81-e84. doi: 10.1016/j.jcjo.2018.06.012. Epub 2018 Aug 31.
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Complete recovery of visual acuity as the main goal of treatment in patients with dysthyroid optic neuropathy.将恢复视力作为甲状腺功能异常性视神经病变患者治疗的主要目标。
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Optic nerve lymphoma: report of two cases and review of the literature.视神经淋巴瘤:两例报告及文献复习
Surv Ophthalmol. 2015 Mar-Apr;60(2):153-65. doi: 10.1016/j.survophthal.2014.11.004. Epub 2014 Dec 18.
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Ophthalmic Plast Reconstr Surg. 2011 Nov-Dec;27(6):471-6. doi: 10.1097/IOP.0b013e31822e5c1b.
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