Liu Siqin, Huang Yaowei, Zou Yang, Huang Fanheng, Deng Yiting, Yan Zhenxing, Xie Huifang
Department of Neurology, Zhujiang Hospital, Southern Medical University, 253 Gongye Avenue Middle, Guangzhou City, Guangdong Province 510282, China.
Department of Neurology, Nanfang Hospital, Southern Medical University, 1838 North Guangzhou Avenue, Baiyun District, Guangzhou City, Guangdon Province 510515, China.
Cereb Circ Cogn Behav. 2021 Feb 4;2:100005. doi: 10.1016/j.cccb.2021.100005. eCollection 2021.
This study used a 3.0T high-resolution magnetic resonance imaging approach to explore basilar artery plaque characteristics in patients suffering from acute isolated pontine infarction.
30 consecutive patients suffering from acute isolated pontine infarction were enrolled in this study and underwent examinations including high-resolution MRI assessment of the basilar artery within 7 days following infarction.
The basilar artery plaque burden of 16 patients with paramedian pontine infarction was 0.26±0.085, while the reconstruction index and enhancement rate index values in these patients were 1.097±0.133 and 1.750±0.447, respectively. In the 14 patients suffering from deep pontine infarction, these three values were 0.21±0.055, 0.896±0.223, and 1.285±0.611, respectively.These values differed significantly when comparing patients suffering from paramedian pontine infarction to those suffering from deep pontine infarction.
This study suggests that the characteristics of basilar artery plaques differ between the two subtypes of pontine infarctions, which may account for the differences in prognosis associated with these two infarct subtypes.
本研究采用3.0T高分辨率磁共振成像方法,探讨急性孤立性脑桥梗死患者的基底动脉斑块特征。
本研究纳入30例连续的急性孤立性脑桥梗死患者,在梗死发生后7天内对其进行包括基底动脉高分辨率MRI评估在内的检查。
16例脑桥旁正中梗死患者的基底动脉斑块负荷为0.26±0.085,而这些患者的重构指数和强化率指数值分别为1.097±0.133和1.750±0.447。在14例脑桥深部梗死患者中,这三个值分别为0.21±0.055、0.896±0.223和1.285±0.611。脑桥旁正中梗死患者与脑桥深部梗死患者相比,这些值存在显著差异。
本研究表明,脑桥梗死的两种亚型之间基底动脉斑块特征不同,这可能解释了这两种梗死亚型预后的差异。