Santangelo Gabrielle, Stone Jonathan, Johnson Mahlon, Walter Kevin
Department of Neurosurgery, University of Rochester, Strong Memorial Hospital, Rochester, New York, United States.
Department of Neuropathology, University of Rochester, Strong Memorial Hospital, Rochester, New York, United States.
Surg Neurol Int. 2022 Sep 23;13:435. doi: 10.25259/SNI_750_2022. eCollection 2022.
This report describes a case of an immunocompetent patient with an intradural abscess from . The majority of fungal spine infections, although rare in general, are due to or through systemic fungemia. To date, there have only been two reports of spondylodiscitis from .
A 37-year-old immunocompetent female patient presented to the neurosurgical service for worsening headaches with nausea, vomiting, vision changes, and weight loss. MRI studies showed diffuse leptomeningeal enhancement of the distal spinal cord, conus medullaris, and nerve roots of the cauda equina extending beyond the neural foramina bilaterally. She had persistent symptoms and no clear diagnosis on lumbar puncture or systemic testing therefore L5-S1 laminectomy for an intradural tissue biopsy was performed. During surgery, cultures were taken and grew colonies of .
This organism has been reported rarely in the literature as being an infectious agent, thus diagnosing remains a challenge but should be considered in patients with a suggestive history.
本报告描述了一例免疫功能正常的患者发生硬脊膜内脓肿的病例。大多数真菌性脊柱感染虽然总体上很少见,但多由 或 通过系统性真菌血症引起。迄今为止,仅有两篇关于 引起的脊椎间盘炎的报道。
一名37岁免疫功能正常的女性患者因头痛加重伴恶心、呕吐、视力改变和体重减轻就诊于神经外科。磁共振成像(MRI)研究显示脊髓远端、圆锥和双侧马尾神经根的软脑膜弥漫性强化,超出神经孔。她症状持续,腰椎穿刺或全身检查均无明确诊断,因此进行了L5-S1椎板切除术以获取硬脊膜内组织活检。手术过程中进行了培养,培养出了 的菌落。
这种微生物在文献中作为感染病原体的报道很少,因此诊断仍然具有挑战性,但对于有提示性病史的患者应予以考虑。