School of Medicine, University of Glasgow, Glasgow, UK.
Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.
Int J Geriatr Psychiatry. 2022 Dec;37(12). doi: 10.1002/gps.5836.
Research priority setting aims to collate stakeholder opinion to determine the most pressing research questions. Priority setting exercises influence decisions around research funding, development and policy. We compared published dementia research priority setting exercises from international healthcare systems.
Four multidisciplinary, international, electronic databases were searched for relevant studies (2010 until 2021). Priorities were extracted, coded and assigned to categories using thematic analysis. The Nine Common Themes of Good Practice (9CTGP) and the Reporting guideline for priority setting of health research (REPRISE) checklists were used to assess methodological and reporting quality respectively.
From 265 titles, 10 priority setting exercises (1179 participants, 147 priorities) were included. Studies spanned four continents and the majority included people living with dementia and their care-givers in the priority setting process (68%). Only one paper met all the best practice indicators. Issues around inclusiveness, implementation and evaluation of the priorities were apparent in nine papers. We categorised priorities under eight themes: caregivers (25%, n = 37), support (24%, n = 35), awareness and education (16%, n = 24), drugs and interventions (14%, n = 21), diagnosis (8%, n = 12), pathology (6%, n = 9), research design (5%, n = 7), and prevention (1%, n = 2). Priorities varied by geographical region, with awareness and education of higher priority in low-middle income countries, compared to caregivers and support in high income countries.
Key priorities were identified with some commonality around themes considered of greatest importance. There is scope to improve the process and reporting of priority setting. Priorities differed according to contextual factors and so, priorities specific to one healthcare setting may not be applicable to others.
研究优先级设置旨在整理利益相关者的意见，以确定最紧迫的研究问题。优先级设置会影响研究资金、发展和政策方面的决策。我们比较了来自国际医疗保健系统的已发表的痴呆症研究优先级设置工作。
在四个多学科、国际的电子数据库中搜索了相关研究（2010 年至 2021 年）。使用主题分析提取、编码和分配主题类别。使用《良好实践的 9 个共同主题（9CTGP）》和《健康研究优先级设置报告指南（REPRISE）》检查表分别评估方法学和报告质量。
从 265 个标题中，纳入了 10 项优先级设置工作（1179 名参与者，147 项优先级）。研究跨越了四大洲，大多数研究将痴呆症患者及其护理人员纳入优先级设置过程（68%）。只有一篇论文满足了所有最佳实践指标。在九篇论文中，明显存在包容性、优先级的实施和评估方面的问题。我们将优先级分为八个主题：护理人员（25%，n=37）、支持（24%，n=35）、意识和教育（16%，n=24）、药物和干预措施（14%，n=21）、诊断（8%，n=12）、病理（6%，n=9）、研究设计（5%，n=7）和预防（1%，n=2）。优先级因地理位置而异，中低收入国家对意识和教育的优先级较高，而高收入国家则对护理人员和支持的优先级较高。
确定了关键的优先事项，围绕被认为最重要的主题有一些共同性。有改进优先级设置过程和报告的空间。由于背景因素的不同，因此，一个医疗保健环境的特定优先级可能不适用于其他环境。
