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用薄编码孔径对微焦点 X 射线光斑进行成像。

Imaging a microfocus X-ray focal spot with a thin coded aperture.

机构信息

Institute of Dentistry, Queen Mary University of London, London, E1 4NS, UK.

Microworks GmbH, Schnetzlerstr. 9, 76137, Karlsruhe, Germany.

出版信息

Sci Rep. 2022 Nov 3;12(1):18635. doi: 10.1038/s41598-022-23338-y.

Abstract

Imaging of the focal spot size in X-ray generators can be achieved by means of a pinhole in a highly attenuating material, such as gold. For microfocus generators with spot sizes of only around 10 microns or less, the material must be very thin to avoid an impractical aspect ratio. With a 90 kV source, only 11% attenuation is attained with 5 µm gold. For a pinhole that is smaller than the focal spot, the signal-to-noise ratio (SNR) may be less than 1. To image the focal spot of a medical X-ray generator, a coded aperture has been used previously to reduce the exposure time required, however the same technique does not appear to have been used to increase the SNR when the attenuation is very low. Such a method is used here, using a no-two-holes-touching variation of a modified uniformly redundant array (MURA). In a prototype sample, with only 5 µm gold having 2.75 µm holes, the focal spot of a microfocus X-ray generator used in a micro-CT system could be clearly visualised and quantified. Directionality of the aberrations made focussing of the X-ray spot more intuitive and reduced the time required to obtain an optimal, quantifiable focus.

摘要

X 射线发生器的焦点尺寸可以通过高衰减材料(如金)中的针孔来实现。对于微焦点发生器,焦点尺寸只有约 10 微米或更小,材料必须非常薄,以避免不切实际的纵横比。对于 90kV 的源,只有 5µm 的金才能达到 11%的衰减。对于小于焦点的针孔,信噪比(SNR)可能小于 1。为了对医用 X 射线发生器的焦点进行成像,以前曾使用编码孔径来减少所需的曝光时间,但是当衰减非常低时,似乎没有使用相同的技术来提高 SNR。在这里使用了一种方法,使用了一种修改后的均匀冗余阵列(MURA)的无两孔接触变体。在一个原型样本中,使用只有 5µm 金的 2.75µm 孔,可以清楚地可视化和量化微焦点 X 射线发生器在微 CT 系统中的焦点。像差的方向性使得聚焦 X 射线光斑更加直观,并减少了获得最佳可量化焦点所需的时间。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efbd/9633642/d0dbb635cac9/41598_2022_23338_Fig1_HTML.jpg

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