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利用 COVID-19 疫苗接种来促进丙型肝炎筛查。

Leveraging COVID-19 vaccination to promote hepatitis C screening.

机构信息

Viral Hepatitis Care Network , Toronto , Ontario , Canada.

Toronto Centre for Liver Disease , University Health Network, University of Toronto , Toronto , Ontario , Canada.

出版信息

Hepatol Commun. 2022 Nov 3;7(1):e2101. doi: 10.1002/hep4.2101. eCollection 2023 Jan 1.

Abstract

Health care initiatives, such as hepatitis C virus (HCV) screening, have been greatly overshadowed by the corona virus disease 2019 (COVID-19) pandemic. However, COVID-19 vaccination programs also provide an opportunity to engage with a high volume of people in a health care setting. We collaborated with a large COVID vaccination center to offer HCV point-of-care testing followed by dried blood spot collection for HCV RNA. Additionally, this opportunity was used to evaluate the practical significance of a 5-minute version of the OraQuick HCV antibody test in lieu of the standard 20-minute test. We tested 2317 individuals; 31 were HCV antibody positive and six were RNA positive of which four were treated and reached sustained virological response. Over a third of those surveyed said they would not have participated had the test required 20 minutes. Conclusion : Colocalizing HCV testing and linkage to care at a COVID vaccination clinic was found to be highly feasible; furthermore, a shortened antibody test greatly improves the acceptance of testing.

摘要

医疗保健计划,如丙型肝炎病毒 (HCV) 筛查,在很大程度上被 2019 年冠状病毒病 (COVID-19) 大流行所掩盖。然而,COVID-19 疫苗接种计划也为在医疗环境中与大量人群接触提供了机会。我们与一个大型 COVID 疫苗接种中心合作,提供即时 HCV 检测,然后采集 HCV RNA 的干血斑。此外,这一机会还用于评估 OraQuick HCV 抗体检测 5 分钟版本代替标准 20 分钟检测的实际意义。我们测试了 2317 个人;31 人 HCV 抗体阳性,6 人 HCV RNA 阳性,其中 4 人接受治疗并达到持续病毒学应答。超过三分之一的受访者表示,如果检测需要 20 分钟,他们就不会参加。结论:在 COVID 疫苗接种诊所进行 HCV 检测和与护理的联合发现是高度可行的;此外,缩短抗体检测大大提高了检测的接受度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a389/9827963/7295dd047f4a/hc9-7-e2101-g001.jpg

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