Department of Paediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Acta Paediatr. 2023 Feb;112(2):286-289. doi: 10.1111/apa.16588. Epub 2022 Nov 12.
To analyse the risk of developing serious disease or death due to COVID-19 among patients who underwent heart surgery during childhood.
A retrospective combined register and patient file study. We identified all individuals who had undergone surgery for congenital heart disease in childhood between 1994 and 2019 in our Local Surgical Register that covers half of the Swedish population. This effort was cross-tabulated with the diagnosis of COVID-19 entered in the National Register of Diagnoses in Sweden from 1 March 2020 to 1 March 2021. Severe disease was defined as treatment at an intensive care unit (ICU).
We identified 3950 individuals, and the median age at follow-up was 16 years (1-44). A total of 32 patients were diagnosed with COVID-19. Five of them were hospitalised for more than 2 days (5-32 days). Two adults required treatment at an ICU; both had additional comorbidity and one died. The corresponding number of ICU stays for this age range in Sweden was 2020 approximately 0.13/1000 person-years, reported from The Swedish Intensive Care Registry.
There was no increased rate of severe COVID-19 among individuals who had undergone surgery for congenital heart disease in childhood. Additional comorbidity is related to outcome.
分析儿童期接受心脏手术的患者因 COVID-19 而患严重疾病或死亡的风险。
回顾性联合登记和患者病历研究。我们在涵盖瑞典人口一半的本地手术登记处中，确定了在 1994 年至 2019 年间接受先天性心脏病手术的所有个体。这项工作与从 2020 年 3 月 1 日至 2021 年 3 月 1 日在瑞典国家诊断登记处输入的 COVID-19 诊断进行了交叉制表。严重疾病定义为在重症监护病房（ICU）接受治疗。
我们确定了 3950 名个体，随访的中位年龄为 16 岁（1-44 岁）。共有 32 名患者被诊断出患有 COVID-19。其中 5 人因住院超过 2 天（5-32 天）。2 名成年人需要在 ICU 接受治疗；两者均有额外的合并症，其中 1 人死亡。在瑞典，该年龄组的 ICU 入住人数约为 2020 年 0.13/1000 人年，来自瑞典重症监护登记处报告。
儿童期接受先天性心脏病手术的个体 COVID-19 严重感染率没有增加。额外的合并症与结果有关。
