Children's Medical Center, Showa University Northern Yokohama Hospital, Yokohama-shi, Kanagawa, Japan.
Department of Pediatrics, Showa University Fujigaoka Hospital, Yokohama-shi, Kanagawa, Japan.
Pediatr Int. 2022 Jan;64(1):e15328. doi: 10.1111/ped.15328.
In monosymptomatic nocturnal enuresis (MNE) treatment, enuretic alarm devices are the first recommended treatment option. This study aimed to compare retrospectively the effectiveness of wearable wireless and wired alarm devices for MNE treatment in children aged 6-14 years.
All children aged 6-16 with MNE who underwent alarm therapy as outpatients were included. A wired alarm device was used from 2012 to 2015, and a wireless alarm device was used from 2016 to 2019. The primary outcomes were the dropout rates during therapy and at last follow up. The full response(14 consecutive dry nights) and the partial response rate during therapy were also assessed.
Of the 173 patients enrolled, 75 and 98 used a wired and a wireless alarm device, respectively. The dropout rate at the last visit was significantly lower in the wireless alarm group than that in the wired alarm group (6.1% vs. 20.0%; P = 0.006). The full response(FR) rate was significantly higher in the wireless alarm group than these in the wired alarm group at 4, 12, 24 weeks (4 weeks: 11.2% vs. 1.3%, P = 0.011; 12 weeks: 31.9% vs. 13.5%, P = 0.005; 24 weeks: 72.9% vs. 39.7%, P < 0.0001).
Wireless alarm therapy for MNE had lower attrition rates and a higher rate of FR than wired alarm therapy.
在单症状性夜间遗尿症（MNE）治疗中，遗尿报警器是首选的治疗方法。本研究旨在回顾性比较 6-14 岁儿童使用可穿戴无线和有线报警器治疗 MNE 的效果。
所有 6-16 岁的 MNE 患儿均接受门诊报警器治疗。2012 年至 2015 年使用有线报警器，2016 年至 2019 年使用无线报警器。主要结局是治疗期间和最后随访时的脱落率。还评估了治疗期间的完全缓解（14 个连续干燥夜晚）和部分缓解率。
在纳入的 173 例患者中，75 例和 98 例分别使用有线和无线报警器。无线报警器组的最后一次随访时的脱落率明显低于有线报警器组（6.1%比 20.0%；P = 0.006）。无线报警器组的完全缓解（FR）率在 4、12、24 周时明显高于有线报警器组（4 周：11.2%比 1.3%，P = 0.011；12 周：31.9%比 13.5%，P = 0.005；24 周：72.9%比 39.7%，P < 0.0001）。
与有线报警器治疗相比，无线报警器治疗 MNE 的脱落率更低，完全缓解率更高。
