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无阿片类药物麻醉:利弊分析。

Opioid-Free Anesthesia: The Pros and Cons.

机构信息

Department of Anesthesiology & Perioperative Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; Ronald Reagan UCLA Medical Center, 757 Westwood Plaza, Suite 3325, Los Angeles, CA 90095-7403, USA.

Department of Anesthesiology & Perioperative Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; Ronald Reagan UCLA Medical Center, 757 Westwood Plaza, Suite 3325, Los Angeles, CA 90095-7403, USA.

出版信息

Adv Anesth. 2022 Dec;40(1):149-166. doi: 10.1016/j.aan.2022.07.003.

Abstract

Appropriate perioperative pain control is essential to aid in patients' recovery after surgery; however, acute postsurgical pain remains poorly treated and there continues to be an overreliance on opiates. Perioperative pain control starts in the operating room, and opiate-free anesthesia (OFA), where no opiates are used intraoperatively, has been proposed as a feasible strategy to further minimize opiates in the perioperative period. In this article, we address the potential benefits and shortcomings of OFA, while exploring tools available to accomplish multimodal anesthesia and ideally OFA, and the evidence behind the techniques proposed.

摘要

适当的围手术期疼痛控制对于促进患者术后康复至关重要;然而,急性术后疼痛仍然治疗效果不佳,并且仍然过度依赖阿片类药物。围手术期疼痛控制始于手术室,而不使用阿片类药物的麻醉(OFA)被提议作为一种可行的策略,以进一步减少围手术期的阿片类药物使用。在本文中,我们将讨论 OFA 的潜在益处和缺点,同时探讨实现多模式麻醉、理想的 OFA 以及所提出技术背后的证据的可用工具。

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