Changal Khalid, Devarasetty Pratyush Pavan, Royfman Rachel, Veria Spiro, Yassen Mohammad, Vyas Rohit, Gössl Mario
Cardiovascular Medicine, University of Toledo College of Medicine and Life Sciences, Ohio, USA.
Valve Science Center, Minneapolis Heart Institute, Abbott Northwestern Hospital, part of Allina Health, Minneapolis, USA.
J Card Surg. 2022 Dec;37(12):5336-5340. doi: 10.1111/jocs.17130. Epub 2022 Nov 6.
The standard practice for management for asymptomatic severe aortic stenosis with a normal left ventricular systolic function is conservative management with a few exceptions. This practice is challenged by two recent randomized controlled trials (RCT). All the prior data is observational. We performed a meta-analysis of these 2 RCTs to determine if early surgical aortic valve replacement in this patient population is beneficial compared with the standard conservative therapy.
对于无症状且左心室收缩功能正常的重度主动脉瓣狭窄患者，标准的管理方法是保守治疗，但有一些例外情况。这种做法受到了最近两项随机对照试验（RCT）的挑战。所有先前的数据都是观察性的。我们对这两项RCT进行了荟萃分析，以确定在该患者群体中，早期手术主动脉瓣置换术与标准保守治疗相比是否有益。
