Michigan State University Veterinary Medical Center, 736 Wilson Road, East Lansing, MI 48824, USA.
School of Veterinary Medicine, University of Wisconsin-Madison, 2015 Linden Drive, Madison, WI 53706, USA.
Vet Clin North Am Small Anim Pract. 2022 Nov;52(6):1163-1192. doi: 10.1016/j.cvsm.2022.06.006.
The unique virulence factors of Bartonella spp make them stealth pathogens that evade the immune system and cause persistent infections that are often difficult to diagnose and treat. Understanding these pathogenic mechanisms allows clinicians to recognize when to pursue diagnostics, how to optimize diagnostic testing and treatment, and ultimately can lead to improved outcomes.
巴尔通体属的独特毒力因子使它们成为能够逃避免疫系统并导致持续感染的隐匿性病原体,而这些感染常常难以诊断和治疗。了解这些发病机制可使临床医生认识到何时需要进行诊断,如何优化诊断检测和治疗,最终可改善治疗结果。