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腹腔镜横腹肌腱膜平面阻滞可减少腹腔镜胆囊切除术后阿片类药物的需求。

Laparoscopic transversus abdominis plane block reduces postoperative opioid requirements after laparoscopic cholecystectomy.

机构信息

Department of Surgery, MetroHealth Medical Center, Cleveland, OH.

Department of Surgery, MetroHealth Medical Center, Cleveland, OH; Case Western Reserve University School of Medicine, Cleveland, OH.

出版信息

Surgery. 2023 Mar;173(3):864-869. doi: 10.1016/j.surg.2022.07.053. Epub 2022 Nov 3.

Abstract

BACKGROUND

Surgeons directly contribute to the over-prescription of opioids. Alternative postoperative pain management strategies are necessary to reduce opioid dispensation and combat the opioid epidemic. We set out to examine the effectiveness of a laparoscopic transversus abdominis plane block on reducing opioid requirements after laparoscopic cholecystectomy.

METHODS

In a retrospective cohort analysis, we compared opioid naïve patients who underwent an elective, outpatient laparoscopic cholecystectomy with a transversus abdominis plane block with patients who underwent a laparoscopic cholecystectomy alone between January 2018 and June 2021 at a single institution. Patient characteristics, perioperative pain scores, and postoperative analgesic requirements were compared between cohorts.

RESULTS

There were 200 patients included in the study (laparoscopic cholecystectomy with a transversus abdominis plane block, n = 100; laparoscopic cholecystectomy alone, n = 100). The average postoperative pain scores in the postanesthesia care unit were equivalent between the groups (laparoscopic cholecystectomy with a transversus abdominis plane block = 3.39 versus laparoscopic cholecystectomy alone = 4.17, P = .12), with the mean postanesthesia care unit opioid requirements significantly lower in patients receiving laparoscopic cholecystectomy with a transversus abdominis plane block (12.1 vs 20.4 oral morphine equivalents, P < .001). Patients receiving laparoscopic cholecystectomy with a transversus abdominis plane block were prescribed fewer opioids on discharge (mean 77.5 vs 92.9 oral morphine equivalents, P < .05) and reported using a lower proportion of their opioid prescription at follow-up (83.2% vs 100%, P < .001). Of the patients receiving laparoscopic cholecystectomy with a transversus abdominis plane block, 65% reported using over-the-counter pain medications compared with 82% of patients receiving laparoscopic cholecystectomy alone (P < .001).

CONCLUSION

Performing a laparoscopic transversus abdominis plane block during elective laparoscopic cholecystectomy is a safe and effective strategy to reduce postoperative opioid requirements for the treatment of acute postoperative pain.

摘要

背景

外科医生直接导致了阿片类药物的过度处方。有必要采用替代的术后疼痛管理策略,以减少阿片类药物的发放,并应对阿片类药物流行。我们旨在研究腹腔镜腹横肌平面阻滞对减少腹腔镜胆囊切除术后阿片类药物需求的有效性。

方法

在回顾性队列分析中,我们比较了 2018 年 1 月至 2021 年 6 月期间在一家机构接受择期门诊腹腔镜胆囊切除术和腹横肌平面阻滞的阿片类药物初治患者与仅接受腹腔镜胆囊切除术的患者。比较了两组患者的特征、围手术期疼痛评分和术后镇痛需求。

结果

本研究纳入了 200 例患者(腹腔镜胆囊切除术联合腹横肌平面阻滞,n=100;腹腔镜胆囊切除术,n=100)。两组患者在麻醉后护理单元的平均术后疼痛评分相当(腹腔镜胆囊切除术联合腹横肌平面阻滞=3.39,腹腔镜胆囊切除术单独=4.17,P=.12),接受腹腔镜胆囊切除术联合腹横肌平面阻滞的患者术后麻醉后护理单元的阿片类药物需求量明显较低(12.1 对 20.4 口服吗啡当量,P<0.001)。接受腹腔镜胆囊切除术联合腹横肌平面阻滞的患者出院时开的阿片类药物较少(平均 77.5 对 92.9 口服吗啡当量,P<0.05),在随访时使用的阿片类药物比例较低(83.2%对 100%,P<0.001)。在接受腹腔镜胆囊切除术联合腹横肌平面阻滞的患者中,65%的患者报告使用了非处方止痛药,而接受单独腹腔镜胆囊切除术的患者为 82%(P<0.001)。

结论

在择期腹腔镜胆囊切除术中行腹腔镜腹横肌平面阻滞是一种安全有效的策略,可减少术后阿片类药物的需求,以治疗急性术后疼痛。

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