非特指弥漫性大 B 细胞淋巴瘤中细胞角蛋白和 CD56 的异常共表达，经细针穿刺抽吸细胞学检查误诊为转移性神经内分泌癌。
Cytokeratin and CD56 aberrant co-expression in diffuse large B-cell lymphoma, NOS misinterpreted as metastatic neuroendocrine carcinoma by FNAC.
机构信息
Department of Cytopathology, Institute of Oncology Ljubljana, Ljubljana, Slovenia.
Department of Pathology, Institute of Oncology Ljubljana, Ljubljana, Slovenia.
出版信息
Cytopathology. 2023 Mar;34(2):165-168. doi: 10.1111/cyt.13190. Epub 2022 Dec 7.
Abstract
Aberrant expression of epithelial and neuroendocrine markers is rare in diffuse large B-cell lymphoma (DLBCL) and can lead to erroneous diagnosis with inappropriate treatment. This case report describes a case of DLBCL with a co-expression of cytokeratins and CD56 that was misdiagnosed as metastatic neuroendocrine carcinoma.
摘要
上皮和神经内分泌标志物在弥漫性大 B 细胞淋巴瘤 (DLBCL) 中表达异常较为罕见，可能导致误诊并进行不适当的治疗。本病例报告描述了一例伴有细胞角蛋白和 CD56 共表达的 DLBCL，误诊为转移性神经内分泌癌。
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