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Inhibitory effect of carp muscle trypsin inhibitor on mammalian pancreatic proteinases.

作者信息

Toyohara H, Makinodan Y

出版信息

Comp Biochem Physiol B. 1986;83(2):283-5. doi: 10.1016/0305-0491(86)90367-6.

DOI:10.1016/0305-0491(86)90367-6
PMID:3633776
Abstract

Carp muscle trypsin inhibitor showed an inhibitory effect on bovine trypsin, bovine alpha-chymotrypsin and porcine elastase in a non-competitive, competitive and competitive manner, respectively. The inhibitor formed a stable complex with the above proteinases which was not dissociated in the presence of 2-mercaptoethanol and SDS. The true target proteinase for carp muscle trypsin inhibitor, as yet unknown, seems to be an alpha-chymotrypsin- or elastase-like enzyme rather than trypsin, judging from the manner of inhibition.

摘要

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